Name | N acetyltransferase |
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Synonyms | AAC 2; NAT2; AAC2; ARY 2; ARY2; Arylamide acetylase 2; Arylamine N acetyltransferase 2; N acetyltransferase… |
Name | glyphosate |
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CAS |
PubMed | Abstract | RScore(About this table) | |
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17272278 | Siehl DL, Castle LA, Gorton R, Keenan RJ: The molecular basis of glyphosate resistance by an optimized microbial acetyltransferase. J Biol Chem. 2007 Apr 13;282(15):11446-55. Epub 2007 Feb 1. GAT is an N-acetyltransferase from Bacillus licheniformis that was optimized by gene shuffling for acetylation of the broad spectrum herbicide, glyphosate, forming the basis of a novel mechanism of glyphosate tolerance in transgenic plants (Castle, L. |
32(0,1,1,2) | Details |
16621678 | Johannes TW, Zhao H: Directed evolution of enzymes and biosynthetic pathways. Curr Opin Microbiol. 2006 Jun;9(3):261-7. Epub 2006 Apr 18. Recent advances have focused on applying directed evolution to a variety of enzymes, such as epoxide hydrolase, glyphosate N-acetyltransferase, xylanase and phosphotriesterase, in order to improve their activity, selectivity, stability and solubility. |
6(0,0,1,1) | Details |
15155947 | Castle LA, Siehl DL, Gorton R, Patten PA, Chen YH, Bertain S, Cho HJ, Duck N, Wong J, Liu D, Lassner MW: Discovery and directed evolution of a glyphosate tolerance gene. Science. 2004 May 21;304(5674):1151-4. We screened a collection of microbial isolates and discovered enzymes exhibiting glyphosate N-acetyltransferase (GAT) activity. |
6(0,0,1,1) | Details |
16547651 | Tan S, Evans R, Singh B: Herbicidal inhibitors of amino acid biosynthesis and herbicide-tolerant crops. Amino Acids. 2006 Mar;30(2):195-204. Epub 2006 Mar 20. Similarly, bar and pat genes isolated from Streptomyces hygroscopicus and S. viridochromogenes, respectively, have been inserted into plants to encode phosphinothricin N-acetyltransferase to detoxify glufosinate. Glyphosate affects aromatic amino acid biosynthesis by inhibiting 5-enolpyruvylshikimate-3- synthase (EPSPS). |
1(0,0,0,1) | Details |