| Name | glutathione S transferase |
|---|---|
| Synonyms | GST class alpha 2; Gst2; GST class alpha; GST class alpha member 2; GST gamma; GSTA 2; GSTA2; GSTA2 2… |
| Name | glyphosate |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 18790555 | Contardo-Jara V, Klingelmann E, Wiegand C: Bioaccumulation of glyphosate and its formulation Roundup Ultra in Lumbriculus variegatus and its effects on biotransformation and antioxidant enzymes. Environ Pollut. 2009 Jan;157(1):57-63. Epub 2008 Sep 14. Glyphosate and its surfactant POEA caused elevation of biotransformation enzyme soluble glutathione S-transferase at non-toxic concentrations. |
6(0,0,1,1) | Details |
| 15620756 | Rendon-von Osten J, Ortiz-Arana A, Guilhermino L, Soares AM: In vivo evaluation of three biomarkers in the mosquitofish (Gambusia yucatana) exposed to pesticides. Chemosphere. 2005 Feb;58(5):627-36. In this study, the acute toxicity and the in vivo effects of commercial chlorpyrifos, carbofuran and glyphosate formulations on cholinesterase (ChE), glutathione S-transferase (GST) and lactate dehydrogenase (LDH) activities of the mosquitofish (Gambusia yucatana) were investigated. |
6(0,0,1,1) | Details |
| 18755596 | Ahsan N, Lee DG, Lee KW, Alam I, Lee SH, Bahk JD, Lee BH: Glyphosate-induced oxidative stress in rice leaves revealed by proteomic approach. Plant Physiol Biochem. 2008 Dec;46(12):1062-70. Epub 2008 Jul 19. An increased accumulation of antioxidant enzymes including peroxidase, glutathione S-transferase, thioredoxin h-type, nucleoside diphosphate kinase 1, peroxiredoxin and a superoxide dismutase [Cu-Zn] chloroplast precursor in the glyphosate-treated sample suggests that a glyphosate treatment possibly generates oxidative stress in plants. |
6(0,0,1,1) | Details |
| 19419775 | Riaz MA, Poupardin R, Reynaud S, Strode C, Ranson H, David JP: Impact of glyphosate and benzo [a] pyrene on the tolerance of mosquito larvae to chemical insecticides. Aquat Toxicol. 2009 Jun 4;93(1):61-9. Epub 2009 Mar 31. Larval glutathione S-transferases activities were strongly induced after exposure to propoxur and moderately induced after exposure to benzo [a] pyrene and glyphosate. |
6(0,0,1,1) | Details |
| 19910015 | Modesto KA, Martinez CB: Roundup causes oxidative stress in liver and inhibits acetylcholinesterase in muscle and brain of the fish Prochilodus lineatus. Chemosphere. 2010 Jan;78(3):294-9. Epub 2009 Nov 11. After 24 and 96h, fish of RD group showed increased glutathione-S-transferase (GST) activity and lipid peroxidation. |
1(0,0,0,1) | Details |
| 3969683 | Hietanen E, Ahotupa M, Heinonen T, Hamalainen H, Kunnas T, Linnainmaa K, Mantyla E, Vainio H: Enhanced peroxisomal beta-oxidation of fatty acids and glutathione metabolism in rats exposed to phenoxyacetic acids. Toxicology. 1985 Feb;34(2):103-11. Peroxisomal beta-oxidation of fatty acids and the activities of -metabolizing enzymes in rat liver were measured after administration of 2,4-dichlorophenoxyacetic acid (2,4-D), 4-chloro-2-methylphenoxyacetic acid (MCPA), clofibrate [ethyl], 2-(p-chlorophenoxy)- glyphosate (N-phosphonomethyl a herbicide not structurally related to phenoxy acids) or saline for 14 days. beta-Oxidation increased by 6-fold in the group given clofibrate, 3-fold in the 2,4-D-treated group, and 2-fold in the MCPA-treated group over the level in the controls (saline-treated). A slight decrease in glutathione S-transferase activity was found in the group treated with clofibrate. |
1(0,0,0,1) | Details |
| 6624478 | Hietanen E, Linnainmaa K, Vainio H: Effects of phenoxyherbicides and glyphosate on the hepatic and intestinal biotransformation activities in the rat. Acta Pharmacol Toxicol. 1983 Aug;53(2):103-12. Both 2,4-D and MCPA increased the hepatic epoxide hydrolase activity and decreased the hepatic glutathione S-transferase activity. |
1(0,0,0,1) | Details |
| 19450865 | Lushchak OV, Kubrak OI, Storey JM, Storey KB, Lushchak VI: Low toxic herbicide Roundup induces mild oxidative stress in goldfish tissues. Chemosphere. 2009 Aug;76(7):932-7. Epub 2009 May 17. The formulation of Roundup consists of the herbicide glyphosate as the active ingredient with polyethoxylene amine added as a surfactant. Roundup exposure generally suppressed the activities of superoxide dismutase (SOD), glutathione S-transferase (GST), glutathione reductase and glucose-6-phosphate dehydrogenase in fish tissues. |
1(0,0,0,1) | Details |