| Name | CDK1 |
|---|---|
| Synonyms | CDC 2; CDC2; CDC28A; CDK 1; CDK1; Cdc2 kinase; Cell cycle controller CDC2; Cell division control protein 2 homolog… |
| Name | glyphosate |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 11896679 | Marc J, Mulner-Lorillon O, Boulben S, Hureau D, Durand G, Belle R: Pesticide Roundup provokes cell division dysfunction at the level of CDK1/cyclin B activation. Chem Res Toxicol. 2002 Mar;15(3):326-31. In summary, Roundup affects cell cycle regulation by delaying activation of the CDK1/cyclin B complex, by synergic effect of glyphosate and formulation products. |
90(1,1,2,5) | Details |
| 15375296 | Marc J, Belle R, Morales J, Cormier P, Mulner-Lorillon O: Formulated glyphosate activates the DNA-response checkpoint of the cell cycle leading to the prevention of G2/M transition. Toxicol Sci. 2004 Dec;82(2):436-42. Epub 2004 Sep 16. We show that formulated glyphosate prevented dephosphorylation of Tyr 15 of the cell cycle regulator CDK1/cyclin B in vivo, the end point target of the G2/M cell cycle checkpoint. |
82(1,1,1,2) | Details |