Protein Information

Name caspase (protein family or complex)
Synonyms caspase; caspases

Compound Information

Name EXD
CAS

Reference List

PubMed Abstract RScore(About this table)
10026204 Weidemann A, Paliga K, Durrwang U, Reinhard FB, Schuckert O, Evin G, Masters CL: Proteolytic processing of the Alzheimer's disease amyloid precursor protein within its cytoplasmic domain by caspase-like proteases. J Biol Chem. 1999 Feb 26;274(9):5823-9.

Sequence analysis of the APP cytosolic domain revealed a consensus motif for group III caspases ((IVL) ExD).
10(0,0,1,5) Details
19565021 Zhirnov OP, Syrtzev VV: Influenza virus pathogenicity is determined by caspase cleavage motifs located in the viral proteins. J Mol Genet Med. 2009 Jan 3;3(1):124-32.

8(0,0,0,8) Details
11755217 Ethell DW, Bossy-Wetzel E, Bredesen DE: Caspase 7 can cleave tumor necrosis factor receptor-I (p60) at a non-consensus motif, in vitro. Biochim Biophys Acta. 2001 Dec 19;1541(3):231-8.


We have found that during apoptosis human TNFRI protein is lost in a caspase-dependent manner.
4(0,0,0,4) Details
9218414 Thornberry NA, Rano TA, Peterson EP, Rasper DM, Timkey T, Garcia-Calvo M, Houtzager VM, Nordstrom PA, Roy S, Vaillancourt JP, Chapman KT, Nicholson DW: A combinatorial approach defines specificities of members of the caspase family and granzyme B. J Biol Chem. 1997 Jul 18;272(29):17907-11.

4(0,0,0,4) Details