Protein Information

Name CRM1
Synonyms CRM 1; CRM1; Chromosome region maintenance 1 protein homolog; Exp1; Exportin 1; XPO 1; XPO1; Chromosome region maintenance 1 protein homologs…

Compound Information

Name EXD
CAS

Reference List

PubMed Abstract RScore(About this table)
10215621 Abu-Shaar M, Ryoo HD, Mann RS: Control of the nuclear localization of Extradenticle by competing nuclear import and export signals. Genes Dev. 1999 Apr 15;13(8):935-45.

The activity of this NES is inhibited by the antibiotic Leptomycin B, suggesting that Exd is exported by a CRM1/exportin1-related export pathway.
81(1,1,1,1) Details
12724421 Huang H, Paliouras M, Rambaldi I, Lasko P, Featherstone M: Nonmuscle myosin promotes cytoplasmic localization of PBX. Mol Cell Biol. 2003 May;23(10):3636-45.


First, PBX is actively exported from the nucleus via a CRM1-dependent pathway.
1(0,0,0,1) Details