Protein Information

Name catalase
Synonyms CAT; Catalase; Erythrocyte derived growth promoting factor; Carnitine O acetyltransferase; Carnitine acetylase; Carnitine acetyltransferase; CAT; Catalases…

Compound Information

Name atrazine
CAS

Reference List

PubMed Abstract RScore(About this table)
9839385 Keay RW, McNeil CJ: Separation-free electrochemical immunosensor for rapid determination of atrazine. Biosens Bioelectron. 1998 Oct 15;13(9):963-70.

Any H2O2 formed in the bulk solution by unbound atrazine-GOD conjugate was scavenged by excess catalase thus removing the requirement for a washing step.
81(1,1,1,1) Details
15137633 Liu GS, Xu DM, Wang LM, Li KB, Liu WP: Effect of organic/inorganic compounds on the enzymes in soil under acid rain stress. J Environ Sci. 2004;16(2):177-80.

The main effects of pollutions including acid rain, Cu2+, atrazine and their combined products on the activities of urease, invertin, acid phosphatase and catalase were studied by means of orthogonal test.
81(1,1,1,1) Details
12619284 Liu W, Yang W, Liu H, Chen X: [Influence of atrazine on the tyrosine environment of catalase] . Huan Jing Ke Xue. 2002 Nov;23(6):86-90.
30(0,0,5,5) Details
20083397 Adesiyan AC, Oyejola TO, Abarikwu SO, Oyeyemi MO, Farombi EO: Selenium provides protection to the liver but not the reproductive organs in an atrazine-model of experimental toxicity. Exp Toxicol Pathol. 2010 Jan 16.

Furthermore, hepatic glutathione and lactate dehydrogenase activity increased while epididymal catalase, ascorbate content, hepatic aspartate aminotransferase and glutathione peroxidase activities in all the tissues decreased in the atrazine-treated animals.
8(0,0,1,3) Details
17201197 Syakalima M, Choongo K, Mwenechanya R, Wepener V, Yamasaki M, Maede Y: Pesticide/herbicide pollutants in the Kafue River and a preliminary investigation into their biological effect through catalase levels in fish. Jpn J Vet Res. 2006 Nov;54(2-3):119-28.

The pesticides/herbicides detected in all samples collectively included: Heptachlor, pp'-DDE, Cypermethrin, Chlordane, Toxaphene, Terbufos, Kelthane, Endosulfan, Dieldrin, pp'-DDD, pp'-DDT, Atrazine, Disulfoton, d-trans-Allethrin and Endrin.
6(0,0,0,6) Details
17868770 Contardo-Jara V, Wiegand C: Biotransformation and antioxidant enzymes of Lumbriculus variegates as biomarkers of contaminated sediment exposure. Chemosphere. 2008 Feb;70(10):1879-88. Epub 2007 Sep 14.

The response capacity of the biotransformation system phase II enzyme glutathione-S-transferase (GST) and the oxidative defense enzyme catalase (CAT) to contaminated sediment and atrazine was investigated to establish them as sensitive biomarkers.
6(0,0,1,1) Details
18092879 Qian H, Daniel Sheng G, Liu W, Lu Y, Liu Z, Fu Z: Inhibitory effects of atrazine on Chlorella vulgaris as assessed by real-time polymerase chain reaction. Environ Toxicol Chem. 2008 Jan;27(1):182-7.

The activities of antioxidation enzymes (e.g., superoxide dismutase, peroxidase, and catalase) also increased markedly in the presence of atrazine, with maximum increases of 1.82-, 1.59-, and 2.31-fold, respectively.
6(0,0,1,1) Details
19125545 Song Y, Zhu LS, Xie H, Wang J, Wang JH, Liu W, Dong XL: Effects of atrazine on DNA damage and antioxidative enzymes in Vicia faba. Environ Toxicol Chem. 2009 May;28(5):1059-62.

To evaluate atrazine (2-chloro-4-ethylamino-6-isopropylamino-1,3,5-triazine) ecotoxicology in soil, the effect of atrazine on the activity of antioxidative enzymes (superoxide dismutase [SOD], catalase [CAT], and guaiacol peroxidase [POD]) was investigated in Vicia faba roots.
6(0,0,1,1) Details
20136348 Singh M, Sandhir R, Kiran R: Oxidative stress induced by atrazine in rat erythrocytes: mitigating effect of vitamin E. Toxicol Mech Methods. 2010 Mar;20(3):119-26.

The activities of antioxidant enzymes such as superoxide dismutase, catalase, glutathione peroxidase, and glutathione-s-transferase were found to be increased significantly in the erythrocytes accompanied by a decrease in the activity of the glucose-6-phosophate dehydrogenase, following atrazine exposure.
6(0,0,1,1) Details
20138743 Singh M, Sandhir R, Kiran R: Effects on antioxidant status of liver following atrazine exposure and its attenuation by vitamin E. Exp Toxicol Pathol. 2010 Feb 6.

The activities of antioxidant enzymes: superoxide dismutase, catalase, glutathione peroxidase and glutathione-s-transferase were significantly increased following atrazine administration and vitamin E treatment could restore these activities.
6(0,0,1,1) Details
1694756 Braunbeck T, Gorge G, Storch V, Nagel R: Hepatic steatosis in zebra fish (Brachydanio rerio) induced by long-term exposure to gamma-hexachlorocyclohexane. Ecotoxicol Environ Saf. 1990 Jun;19(3):355-74.

Among several substances tested so far in zebra fish (4-nitrophenol, 4-chloroaniline 3,4-dichloroaniline, atrazine, lindane), lindane is the only compound inducing behavioral changes and hepatic steatosis in conjunction with a reduction in fertility.
Changes in peroxisomes were visualized by cytochemical staining for catalase activity with diaminobenzidine.
2(0,0,0,2) Details
19672647 Abarikwu SO, Adesiyan AC, Oyeloja TO, Oyeyemi MO, Farombi EO: Changes in Sperm Characteristics and Induction of Oxidative Stress in the Testis and Epididymis of Experimental Rats by a Herbicide, Atrazine. Arch Environ Contam Toxicol. 2009 Aug 12.

In comparison to control, glutathione (GSH) and glutathione-S-transferase (GST) activities were elevated in the high-dose group, whereas the activity of superoxide dismutase (SOD), catalase (CAT); ascorbate (AA), and malondialdehyde (MDA) levels and hydrogen peroxide production were unchanged in the testis during the 7-day-exposure protocol.
1(0,0,0,1) Details
19297032 Qian H, Chen W, Li J, Wang J, Zhou Z, Liu W, Fu Z: The effect of exogenous nitric oxide on alleviating herbicide damage in Chlorella vulgaris. Aquat Toxicol. 2009 May 17;92(4):250-7. Epub 2009 Feb 27.

Atrazine (100 microg/L) or glufosinate (10 mg/L) treatment alone or in combination with 20 microM sodium nitroprussiate (SNP, 10 microM with glufosinate) was administered to algae for a short time period of 48 h to observe changes in physiology and gene transcription and expression.
Supplementation also increased chlorophyll content and antioxidant enzymes, superoxide dismutase (SOD), peroxidase (POD) and catalase (CAT) activity, as compared to herbicide treatment alone.
1(0,0,0,1) Details
18973769 Salaberria I, Hansen BH, Asensio V, Olsvik PA, Andersen RA, Jenssen BM: Effects of atrazine on hepatic metabolism and endocrine homeostasis in rainbow trout (Oncorhynchus mykiss). Toxicol Appl Pharmacol. 2009 Jan 1;234(1):98-106. Epub 2008 Oct 10.

Simultaneously we analyzed hepatic gene expression of cytochrome P450 (CYP) 1A and pi-class glutathione S-transferase (GST-P), and catalase (CAT) activity.
1(0,0,0,1) Details
16777423 Nemat Alla MM, Hassan NM: Changes of antioxidants levels in two maize lines following atrazine treatments. Plant Physiol Biochem. 2006 Apr;44(4):202-10. Epub 2006 Jun 5.

Meanwhile, ascorbic acid (AsA) and reduced glutathione (GSH) contents were significantly decreased along with significant inhibitions in activities of superoxide dismutase (SOD; EC 1.15.1.1), catalase (CAT; EC 1.11.1.6), ascorbate peroxidase (APX; EC 1.11.1.7), guaiacol peroxidase (GPX; EC 1.11.1.7), and glutathione-S-transferase (GST; EC 2.5.1.18).
1(0,0,0,1) Details
16510128 Patel S, Singh V, Kumar A, Gupta YK, Singh MP: Status of antioxidant defense system and expression of toxicant responsive genes in striatum of maneb- and paraquat-induced Parkinson's disease phenotype in mouse: mechanism of neurodegeneration. Brain Res. 2006 Apr 7;1081(1):9-18. Epub 2006 Feb 28.

The involvement of cytochrome P4502E1 and glutathione S-transferases A4-4 enzymes in the detoxification of several pesticides such as atrazine, fenamirol, organophosphorous insecticide parathion, methoxychlor, diethyl dithiocarbamate and paraquat has been known.
A significant increase in catalase, glutathione S-transferase and lipid peroxidation in the striatum was found following 3, 6 and 9 weeks of co-treatment as compared with individual treatment or controls.
1(0,0,0,1) Details