Protein Information

Name IL 5
Synonyms B cell differentiation factor 1; B cell differentiation factor I; EDF; Eosinophil differentiation factor; IL 5; IL5; Interleukin 5; Interleukin 5 precursor…

Compound Information

Name atrazine
CAS

Reference List

PubMed Abstract RScore(About this table)
10883730 Hooghe RJ, Devos S, Hooghe-Peters EL: Effects of selected herbicides on cytokine production in vitro. Life Sci. 2000 May 19;66(26):2519-25.

After in vitro exposure of human peripheral blood mononuclear cells from normal donors, the production of all 3 cytokines tested--interferon-gamma (a type 1 cytokine), interleukin-5 (a type 2 cytokine) and tumor necrosis factor-alpha (an inflammatory cytokine)--was impaired by up to 70, 50 and 70% respectively in a concentration-dependent manner in cultures exposed to atrazine (0.03-3 microM in 1% dimethylsulfoxide, DMSO).		 31(0,1,1,1) Details
15319175 Devos S, Van Den Heuvel R, Hooghe R, Hooghe-Peters EL: Limited effect of selected organic pollutants on cytokine production by peripheral blood leukocytes. Eur Cytokine Netw. 2004 Apr-Jun;15(2):145-51.

Lindane and atrazine reduced both IL-5 and IFN-gamma.		 83(1,1,1,3) Details