| Name | CYP1A2 |
|---|---|
| Synonyms | CP12; CYP1A2; CYPIA 2; CYPIA2; Cytochrome P450 1A2; Dioxin inducible P3 450; P(3)450; P3 450… |
| Name | atrazine |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 14727741 | Bode M, Stobe P, Thiede B, Schuphan I, Schmidt B: Biotransformation of atrazine in transgenic tobacco cell culture expressing human P450. Pest Manag Sci. 2004 Jan;60(1):49-58. The results showed that both foreign enzymes CYP1A1 and CYP1A2 catalyse N-dealkylation of atrazine. |
84(1,1,1,4) | Details |
| 11129571 | Shiota N, Kodama S, Inui H, Ohkawa H: Expression of human cytochromes P450 1A1 and P450 1A2 as fused enzymes with yeast -cytochrome P450 oxidoreductase in transgenic tobacco plants. Biosci Biotechnol Biochem. 2000 Oct;64(10):2025-33. Among 11 isoforms of the human cytochrome P450 enzymes metabolizing xenobiotics, CYP 1A1 and CYP 1A2 were major P450 species in the metabolism of the herbicides chlortoluron and atrazine in a yeast expression system. CYP1A2 was more active in the metabolism of both herbicides than CYP1A1. |
4(0,0,0,4) | Details |
| 9711812 | Hanioka N, Jinno H, Tanaka-Kagawa T, Nishimura T, Ando M: Changes in rat liver cytochrome P450 enzymes by atrazine and simazine treatment. Xenobiotica. 1998 Jul;28(7):683-98. Immunoblotting showed that only simazine induces CYP1A2 and CYP4A1/2 protein expression. 4. |
1(0,0,0,1) | Details |
| 9305587 | Lang DH, Rettie AE, Bocker RH: Identification of enzymes involved in the metabolism of atrazine, terbuthylazine, ametryne, and terbutryne in human liver microsomes. Chem Res Toxicol. 1997 Sep;10(9):1037-44. A highly significant correlation in the high-affinity concentration range was seen with cytochrome P450 1A2 activities. |
1(0,0,0,1) | Details |
| 9920461 | Hanioka N, Jinno H, Kitazawa K, Tanaka-Kagawa T, Nishimura T, Ando M, Ogawa K: In vitro biotransformation of atrazine by rat liver microsomal cytochrome P450 enzymes. Chem Biol Interact. 1998 Nov 27;116(3):181-98. |
0(0,0,0,0) | Details |