| Name | glutathione S transferase P |
|---|---|
| Synonyms | DFN 7; PI; DFN7; FAEES 3; FAEES3; GST class pi; GST3; GSTP 1… |
| Name | atrazine |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 15115887 | Abel EL, Opp SM, Verlinde CL, Bammler TK, Eaton DL: Characterization of atrazine biotransformation by human and murine glutathione S-transferases. Toxicol Sci. 2004 Aug;80(2):230-8. Epub 2004 Apr 28. Docking studies of the atrazine-GST conjugate in the hGSTP1-1 substrate-binding site were used to elucidate a basis for the dramatic difference in activity between mouse GSTP1-1 and GSTP2-2 (7.14 versus 0.02 nmol/min/mg protein, respectively). |
162(2,2,2,2) | Details |
| 18973769 | Salaberria I, Hansen BH, Asensio V, Olsvik PA, Andersen RA, Jenssen BM: Effects of atrazine on hepatic metabolism and endocrine homeostasis in rainbow trout (Oncorhynchus mykiss). Toxicol Appl Pharmacol. 2009 Jan 1;234(1):98-106. Epub 2008 Oct 10. Simultaneously we analyzed hepatic gene expression of cytochrome P450 (CYP) 1A and pi-class glutathione S-transferase (GST-P), and catalase (CAT) activity. |
1(0,0,0,1) | Details |
| 19126423 | Perez-Carreon JI, Dargent C, Merhi M, Fattel-Fazenda S, Arce-Popoca E, Villa-Trevino S, Rouimi P: Tumor promoting and co-carcinogenic effects in medium-term rat hepatocarcinogenesis are not modified by co-administration of 12 pesticides in mixture at acceptable daily intake. Food Chem Toxicol. 2009 Mar;47(3):540-6. Epub 2008 Dec 24. We performed a 12 commercially available pesticides combination with alachlor, atrazine, carbofuran, chlorpyrifos, diazinon, dicofol, endosulfan, iprodione, mancozeb, maneb, procymidone and rotenone. Co-carcinogenic effect and promoting activity were evaluated using gamma-glutamyl transpeptidase (GGT) positive altered hepatocyte foci, as well, protein and mRNA levels of glutathione S-transferase P (GSTP) in liver extracts as molecular biomarkers of carcinogenic effects. |
1(0,0,0,1) | Details |