Protein Information

Name acetolactate synthase
Synonyms Acetolactate synthase; OR10B1P

Compound Information

Name atrazine
CAS

Reference List

PubMed Abstract RScore(About this table)
12687370 Sibony M, Rubin B: Molecular basis for multiple resistance to acetolactate synthase-inhibiting herbicides and atrazine in Amaranthus blitoides (prostrate pigweed). Planta. 2003 Apr;216(6):1022-7. Epub 2002 Dec 18.
82(1,1,1,2) Details
11341696 Leboulanger C, Rimet F, de Lacotte M, Berard A: Effects of atrazine and nicosulfuron on freshwater microalgae. Environ Int. 2001 Jan;26(3):131-5.

Atrazine and nicosulfuron have different targets in plant metabolism, respectively, photosystem II (PSII) and acetolactate synthase (ALS), and the expected effects were different.
81(1,1,1,1) Details
10188206 Short P, Colborn T: Pesticide use in the U.S. and policy implications: a focus on herbicides. Toxicol Ind Health. 1999 Jan-Mar;15(1-2):240-75.

Acetolactate synthase (ALS) inhibitors, namely the sulfonylureas and imidazolinones, are one of the fastest growing classes of herbicides.
Atrazine is the predominant herbicide used according to poundage, with 68-73 million lbs of AIs applied in 1995.
1(0,0,0,1) Details
16406601 Ma J, Wang S, Wang P, Ma L, Chen X, Xu R: Toxicity assessment of 40 herbicides to the green alga Raphidocelis subcapitata. Ecotoxicol Environ Saf. 2006 Mar;63(3):456-62.

The most toxic herbicides were atrazine, ametryme, simazine, prometryne, cyanazine, isoproturon, chlorotoluron, diuron, methabenzthiazuron, and paraquat.
The descending order of the average acute toxicity to R. subcapitata of herbicides with regard to the nine modes of action was as follows: photosynthetic process> cell division> lipid synthesis, acetyl-coenzyme A carboxylase> acetolactate synthase> 5-enolpyruvyl-shikimate-3-phosphate synthase, glutamine synthase, hormone synthesis> protoporphyrinogen oxidase.
1(0,0,0,1) Details