| Name | CYP2E1 |
|---|---|
| Synonyms | CPE 1; Flavoprotein linked monooxygenase; Xenobiotic monooxygenase; Microsomal monooxygenase; CPE1; CYP2E; CYP2E1; CYP2E1 protein… |
| Name | amitrole |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 10579652 | Huentelman MJ, Peters CM, Ervine WE, Polutnik SM, Johnson P: has differential effects on rat neuron and thymocyte reactive species levels and cell viability. Comp Biochem Physiol C Pharmacol Toxicol Endocrinol. 1999 Sep;124(1):83-9. These parameters in neurons were relatively unaffected when the cells were incubated with in the presence of inhibitors of -oxidizing enzymes, but in thymocytes, the presence of diallyl sulfide (an inhibitor of -inducible cytochrome P450, CYP2E1) or 4-methylpyrazole (an inhibitor of CYP2E1 and alcohol dehydrogenase) caused decreases in ROS production from |
1(0,0,0,1) | Details |
| 10607376 | Fort DJ, Stover EL, Bantle JA, Finch RA: Evaluation of the developmental toxicity of thalidomide using frog embryo teratogenesis assay-xenopus (FETAX): biotransformation and detoxification. Teratog Carcinog Mutagen. 2000;20(1):35-47. Results obtained indicated that thalidomide was predominantly activated by P-450 isozyne CYP2E1, although weak cross-specificity between CYP1A1/A2 may have existed. |
1(0,0,0,1) | Details |
| 2133088 | Koop DR: Inhibition of -inducible cytochrome P450IIE1 by 3-amino-1,2,4-triazole. Chem Res Toxicol. 1990 Jul-Aug;3(4):377-83. |
1(0,0,0,1) | Details |
| 9698299 | Su T, He W, Gu J, Lipinskas TW, Ding X: Differential xenobiotic induction of CYP2A5 in mouse liver, kidney, lung, and olfactory mucosa. Drug Metab Dispos. 1998 Aug;26(8):822-4. On the other hand, pyrazole treatment induced CYP2E1 in the olfactory mucosa as well as in liver and kidney, indicating that the olfactory mucosa was exposed to pyrazole. |
1(0,0,0,1) | Details |