| Name | tumor necrosis factor alpha |
|---|---|
| Synonyms | Cachectin; DIF; TNF; TNF alpha; TNF a; TNFA; TNFSF 2; TNFSF2… |
| Name | amitrole |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 1911044 | Shau HY: Red cell regulation of tumor necrosis factor-induced human neutrophil cytostatic activity. Cancer Commun. 1991 Sep;3(9):283-6. |
2(0,0,0,2) | Details |
| 1567224 | Royall JA, Gwin PD, Parks DA, Freeman BA: Responses of vascular endothelial oxidant metabolism to lipopolysaccharide and tumor necrosis factor-alpha. Arch Biochem Biophys. 1992 May 1;294(2):686-94. |
2(0,0,0,2) | Details |
| 9685387 | Singh I, Pahan K, Khan M, Singh AK: Cytokine-mediated induction of production is redox-sensitive. J Biol Chem. 1998 Aug 7;273(32):20354-62. Treatment of rat primary astrocytes with tumor necrosis factor-alpha (TNF-alpha) or interleukin-1beta led to marked alteration in cellular redox (decrease in intracellular GSH) and rapid degradation of SM to |
1(0,0,0,1) | Details |
| 14962975 | Carter AB, Tephly LA, Venkataraman S, Oberley LW, Zhang Y, Buettner GR, Spitz DR, Hunninghake GW: High levels of catalase and peroxidase activity dampen H2O2 signaling in human alveolar macrophages. Am J Respir Cell Mol Biol. 2004 Jul;31(1):43-53. Epub 2004 Feb 12. Results are presented which support the hypothesis that adequate steady-state levels of peroxide (H2O2) are required to overcome the effects of high catalase and peroxidase (GPx) expression for p38 mitogen-activated protein (MAP) kinase activation and tumor necrosis factor (TNF)-alpha gene expression in human alveolar macrophages stimulated with asbestos. |
1(0,0,0,1) | Details |
| 16910777 | Dasgupta J, Subbaram S, Connor KM, Rodriguez AM, Tirosh O, Beckman JS, Jourd'Heuil D, Melendez JA: Manganese superoxide dismutase protects from TNF-alpha-induced apoptosis by increasing the steady-state production of H2O2. Antioxid Redox Signal. 2006 Jul-Aug;8(7-8):1295-305. Here we demonstrate that the antiapoptotic effects of SOD2 are attributed to its ability to generate H (2) O (2) and that its efficient removal resensitizes cells to tumor necrosis factor (TNF)-alpha-induced apoptosis. |
1(0,0,0,1) | Details |
| 1316135 | Morland CM, Wilson SJ, Holgate ST, Roche WR: Selective eosinophil leukocyte recruitment by transendothelial migration and not by leukocyte-endothelial cell adhesion. Am J Respir Cell Mol Biol. 1992 May;6(5):557-66. First, the adherence of eosinophils and neutrophils to ECs stimulated with lipopolysaccharide, interleukin (IL)-1 alpha, and tumor necrosis factor-alpha were compared. |
1(0,0,0,1) | Details |
| 7946385 | Kinnula VL, Yankaskas JR, Chang L, Virtanen I, Linnala A, Kang BH, Crapo JD: Primary and immortalized (BEAS 2B) human bronchial epithelial cells have significant antioxidative capacity in vitro. Am J Respir Cell Mol Biol. 1994 Nov;11(5):568-76. Although Mn SOD was low in BEAS 2B cells, it could be significantly induced by tumor necrosis factor treatment. |
1(0,0,0,1) | Details |
| 12775721 | Chovolou Y, Watjen W, Kampkotter A, Kahl R: Resistance to tumor necrosis factor-alpha (TNF-alpha)-induced apoptosis in rat hepatoma cells expressing TNF-alpha is linked to low antioxidant enzyme expression. J Biol Chem. 2003 Aug 8;278(32):29626-32. Epub 2003 May 29. |
1(0,0,0,1) | Details |