| Name | lactate dehydrogenase (protein family or complex) |
|---|---|
| Synonyms | LDH; lactate dehydrogenase; lactate dehydrogenases |
| Name | amitrole |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 8168729 | Konorev EA, Struck AT, Baker JE, Ramanujam S, Thomas JP, Radi R, Kalyanaraman B: Intracellular catalase inhibition does not predispose rat heart to ischemia-reperfusion and peroxide-induced injuries. Free Radic Res Commun. 1993;19(6):397-407. The extent of ischemic injury was assessed using postischemic contractile recovery and lactate dehydrogenase (LDH) leakage into reperfusate. |
1(0,0,0,1) | Details |
| 8632155 | Ben-Yoseph O, Boxer PA, Ross BD: Assessment of the role of the and pathways in the protection of primary cerebrocortical cultures from oxidative stress. J Neurochem. 1996 Jun;66(6):2329-37. The antioxidant capacity of these cultures was systematically evaluated using H2O2, and the resultant toxicity was quantified by lactate dehydrogenase release. |
1(0,0,0,1) | Details |
| 7840245 | Salahudeen AK: Role of lipid peroxidation in H2O2-induced renal epithelial (LLC-PK1) cell injury. Am J Physiol. 1995 Jan;268(1 Pt 2):F30-8. In a time course study, lipid peroxidation (thiobarbituric acid reaction) and degradation (release of [3H] preceded H2O2-induced cytolysis (51Cr and lactate dehydrogenase release). |
1(0,0,0,1) | Details |
| 8005512 | Kinnula VL, Aalto K, Raivio KO, Walles S, Linnainmaa K: Cytotoxicity of oxidants and asbestos fibers in cultured human mesothelial cells. Free Radic Biol Med. 1994 Feb;16(2):169-76. Cellular nucleotide depletion, DNA single strand breaks, extracellular release of nucleotides, and their catabolites and lactate dehydrogenase (LDH) were assessed as markers of cell damage after 4-6 h exposure to the oxidants or fibers. |
1(0,0,0,1) | Details |
| 3372170 | Nguyen KP, Chung ML, Anderson PJ, Johnson M, Epstein DL: peroxide removal by the calf aqueous outflow pathway. Invest Ophthalmol Vis Sci. 1988 Jun;29(6):976-81. Using loss of lactate dehydrogenase activity as a measure of cell damage, we found a 30% drop in activity after perfusing with BCNU, diamide, and 3-aminotriazole, followed by 3 hr with 10 mM peroxide.(ABSTRACT TRUNCATED AT 250 WORDS) |
1(0,0,0,1) | Details |
| 14980700 | Hashimoto T, Ibi M, Matsuno K, Nakashima S, Tanigawa T, Yoshikawa T, Yabe-Nishimura C: An endogenous metabolite of acts as a unique cytoprotective agent against oxidative stress-induced injury. Free Radic Biol Med. 2004 Mar 1;36(5):555-64. (O (2)(-)) and H (2) O (2) induced a dose-dependent leakage of lactate dehydrogenase (LDH) and decreased cell viability denoted by MTT assay. |
1(0,0,0,1) | Details |
| 9931285 | Shaikh ZA, Vu TT, Zaman K: Oxidative stress as a mechanism of chronic cadmium-induced hepatotoxicity and renal toxicity and protection by antioxidants. Toxicol Appl Pharmacol. 1999 Feb 1;154(3):256-63. Serum amino transferase and lactate dehydrogenase activities were elevated after 9 weeks of Cd administration, indicating hepatic damage. |
2(0,0,0,2) | Details |
| 8200258 | Ito Y, Suzuki Y, Ogonuki H, Hiraishi H, Razandi M, Terano A, Harada T, Ivey KJ: Role of iron and redox cycle in -induced cytotoxicity to cultured rat hepatocytes. Dig Dis Sci. 1994 Jun;39(6):1257-64. Cytotoxicity was evaluated by measuring 51Cr and lactate dehydrogenase release. |
2(0,0,0,2) | Details |