| Name | NKX2 1 |
|---|---|
| Synonyms | BCH; TEBP; BHC; Homeobox protein NK 2 homolog A; Homeobox protein Nkx 2.1; NK 2; NKX2 1; NKX2.1… |
| Name | amitrole |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 18227016 | Pan HM, Zhang LS, Wu DS: [Effects of amitrole on thyroid hormone-associated gene transcription in FRTL-5 cells]. Nan Fang Yi Ke Da Xue Xue Bao. 2008 Jan;28(1):12-5. OBJECTIVE: To observe the effects of amitrole on the transcription of thyroglobulin (tg), thyroid peroxidase (tpo), Na (+)/I- symporter (nis), Na (+)/I- symporter (nis), thyroid-stimulating hormone receptor (tshr), thyroid transcription factor 1 (ttf-1) and paired-domain protein-8 (pax-8) genes in FRTL-5 cells and investigate the mechanism of amitrole for intervening in thyroid hormone activity. |
31(0,1,1,1) | Details |
| 19581346 | Hoshi S, Hoshi N, Okamoto M, Paiz J, Kusakabe T, Ward JM, Kimura S: Role of NKX2-1 in N-bis (2-hydroxypropyl)-nitrosamine-induced thyroid adenoma in mice. Carcinogenesis. 2009 Sep;30(9):1614-9. Epub 2009 Jul 6. Using this mouse line as compared with wild-type and Nkx2-1 heterozygous mice, a thyroid carcinogenesis study was carried out using the genotoxic carcinogen N-bis (2-hydroxypropyl)-nitrosamine (DHPN), followed by sulfadimethoxine (SDM) or the non-genotoxic carcinogen amitrole (3-amino-1,2,4-triazole). |
11(0,0,1,6) | Details |