Protein Information

Name SP2
Synonyms SP2; Sp2 transcription factor; Transcription factor Sp2; Sp2 transcription factors; Transcription factor Sp2s

Compound Information

Name amitrole
CAS

Reference List

PubMed Abstract RScore(About this table)
11829410 Milton NG: Inhibition of catalase activity with 3-amino-triazole enhances the cytotoxicity of the Alzheimer's amyloid-beta peptide. Neurotoxicology. 2001 Dec;22(6):767-74.


Inhibition of endogenous catalase using 3-amino-1,2,4-triazole (3AT) in neuronal (NT-2) and myeloma (SP2/0-Ag-14) cell lines increases Abeta toxicity, suggesting that any protective role for endogenous catalase requires active enzyme.
1(0,0,0,1) Details