Protein Information

Name interleukin 1
Synonyms Catabolin; IL 1; IL 1 beta; IL 1B; IL1 beta; IL1B; IL1F2; Interleukin 1…

Compound Information

Name amitrole
CAS

Reference List

PubMed Abstract RScore(About this table)
2367521 Brown JM, White CW, Terada LS, Grosso MA, Shanley PF, Mulvin DW, Banerjee A, Whitman GJ, Harken AH, Repine JE: Interleukin 1 pretreatment decreases ischemia/reperfusion injury. Proc Natl Acad Sci U S A. 1990 Jul;87(13):5026-30.

5(0,0,0,5) Details
9037247 Renard P, Zachary MD, Bougelet C, Mirault ME, Haegeman G, Remacle J, Raes M: Effects of antioxidant enzyme modulations on interleukin-1-induced nuclear factor kappa B activation. Biochem Pharmacol. 1997 Jan 24;53(2):149-60.

3(0,0,0,3) Details
9685387 Singh I, Pahan K, Khan M, Singh AK: Cytokine-mediated induction of ceramide production is redox-sensitive. J Biol Chem. 1998 Aug 7;273(32):20354-62.


Treatment of rat primary astrocytes with tumor necrosis factor-alpha (TNF-alpha) or interleukin-1beta led to marked alteration in cellular redox (decrease in intracellular GSH) and rapid degradation of SM to ceramide.
1(0,0,0,1) Details
8865862 Korybalska K, Breborowicz A, Martis L, Oreopoulos DG: In vitro detection of hydrogen peroxide in mesothelial cells. Adv Perit Dial. 1996;12:7-10.


However, interleukin-1 (IL-1) (10 ng/mL) enhances, within two hours (+40%, p < 0.05), intracellular production of hydrogen peroxide.
1(0,0,0,1) Details