Protein Information

Name TLR4
Synonyms CD284; CD284 antigen; TLR 4; TLR4; TOLL; Toll like receptor 4; Toll like receptor 4 precursor; hToll…

Compound Information

Name amitrole
CAS

Reference List

PubMed Abstract RScore(About this table)
19933270 Banerjee S, Zmijewski JW, Lorne E, Liu G, Sha Y, Abraham E: Modulation of SCF beta-TrCP-dependent I kappaB alpha ubiquitination by hydrogen peroxide. J Biol Chem. 2010 Jan 22;285(4):2665-75. Epub 2009 Nov 20.


Recent studies have indicated that increases in intracellular concentrations of hydrogen peroxide (H (2) O (2)) have anti-inflammatory effects in neutrophils, including inhibition of the degradation of I kappaB alpha after TLR4 engagement.
1(0,0,0,1) Details
18177342 Ohnishi T, Yoshida T, Igarashi A, Muroi M, Tanamoto K: Effects of possible endocrine disruptors on MyD88-independent TLR4 signaling. FEMS Immunol Med Microbiol. 2008 Mar;52(2):293-5. Epub 2007 Dec 20.

Aldicarb, amitrole, benzophenone, butyl benzyl phthalate, 2,4-dichlorophenoxy acetic acid, dibutyl phthalate, 2,4-dichlorophenol, dicyclohexyl phthalate, diethylhexyl adipate, diethylhexyl phthalate, dihexyl phthalate, di-n-pentyl phthalate, methomyl, metribuzin, nitrofen, 4-nitrotoluene, permethrin, trifluralin, 2,4,5-trichlorophenoxyacetic acid and vinclozolin had no significant effects at 100 muM.
1(0,0,0,1) Details