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Yang ES, Park JW: Antioxidant enzyme inhibitors enhance nitric oxide-induced cell death in U937 cells. Biochimie. 2006 Jul;88(7):869-78. Epub 2006 Feb 28.
Upon exposure to 1 mM S-nitroso-N-acetylpenicillamine (SNAP), the nitric oxide donor, to U937 cells, the viability was lower and the protein oxidation, lipid peroxidation and oxidative DNA damage reflected by an increase in 8-hydroxy-2'-deoxyguanosine, were higher in inhibitor-treated cells as compared to control cells. |
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