| Name | cytochrome P450 (protein family or complex) |
|---|---|
| Synonyms | cytochrome P450; cytochrome P 450; CYP450; CYP 450 |
| Name | chlorotoluron |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 7925408 | Pierrel MA, Batard Y, Kazmaier M, Mignotte-Vieux C, Durst F, Werck-Reichhart D: Catalytic properties of the plant cytochrome P450 CYP73 expressed in yeast. Eur J Biochem. 1994 Sep 15;224(3):835-44. In addition, it was shown to oxygenate five xenobiotics and mechanism-based inactivators, including the herbicide chlorotoluron. |
1(0,0,0,1) | Details |
| 19402758 | Weil M, Scholz S, Zimmer M, Sacher F, Duis K: Gene expression analysis in zebrafish embryos: a potential approach to predict effect concentrations in the fish early life stage test. Environ Toxicol Chem. 2009 Sep;28(9):1970-8. The effects of 14 substances on lethal and sublethal endpoints of the DarT and on expression of potential marker genes were investigated: the aryl hydrocarbon receptor 2, cytochrome P450 1A (cypla), heat shock protein 70, fizzy-related protein 1, the transcription factors v-maf musculoaponeurotic fibrosarcoma oncogene family protein g (avian) 1 and NF-E2-p45-related factor, and heme oxygenase 1 (hmox1). For 10 (3,4- and 3,5-dichloroaniline, 1,4-dichlorobenzene, 2,4-dinitrophenol, atrazine, parathion-ethyl, chlorotoluron, 4-nitroquinoline-1-oxide, and cadmium) out of the 14 tested substances, LOEC values derived with the Gene-DarT differ by a factor of less than 10 from LOEC values of fish early life stage tests with zebrafish. |
1(0,0,0,1) | Details |
| 16668240 | Donaldson RP, Luster DG: Multiple Forms of Plant Cytochromes P-450. Plant Physiol. 1991 Jul;96(3):669-674. Accumulating evidence indicates that there is a multiplicity of cytochrome P-450 enzymes in plants. Evidence that cytochromes P-450 are involved in the detoxification of herbicides (chlorotoluron, primsulfuron, and diclofop) includes photoreversible CO inhibition of the reactions, and a requirement for O (2) and |
4(0,0,0,4) | Details |
| 19005807 | Schalk M, Pierrel MA, Zimmerlin A, Batard Y, Durst F, Werck-Reichhart D: Xenobiotics: Substrates and inhibitors of the plant cytochrome P450. . Environ Sci Pollut Res Int. 1997;4(4):229-34. Nevertheless, it oxygenates several small and planar xenobiotics with low efficiency, including an herbicide (chlorotoluron). |
2(0,0,0,2) | Details |