Name | lactate dehydrogenase (protein family or complex) |
---|---|
Synonyms | LDH; lactate dehydrogenase; lactate dehydrogenases |
Name | diquat |
---|---|
CAS |
PubMed | Abstract | RScore(About this table) | |
---|---|---|---|
8382845 | Rikans LE, Cai Y: Diquat-induced oxidative damage in BCNU-pretreated hepatocytes of mature and old rats. Toxicol Appl Pharmacol. 1993 Feb;118(2):263-70. The hepatocytes were incubated for 2 hr with 0, 0.5, or 2.0 mM diquat dibromide, and samples were taken at various time points for measurements of thiobarbituric acid reactive substances, lactate dehydrogenase leakage, protein sulfhydryl groups, and protein carbonyl groups. |
6(0,0,1,1) | Details |
1320687 | Rikans LE, Cai Y: Age-associated enhancement of diquat-induced lipid peroxidation and cytotoxicity in isolated rat hepatocytes. J Pharmacol Exp Ther. 1992 Jul;262(1):271-8. Hepatocytes of old rats were more sensitive than those of mature rats to diquat-induced cytotoxicity (lactate dehydrogenase release into the medium). |
6(0,0,1,1) | Details |
7299856 | Kurisaki E, Nagamori H: A comparative study on the effects of paraquat and diquat on cultured human cells. J Toxicol Sci. 1981 Aug;6(3):203-7. Paraquat caused slightly higher lactate dehydrogenase activity than did diquat. |
6(0,0,1,1) | Details |
1327553 | Jaeschke H, Benzick AE: Pathophysiological consequences of enhanced intracellular liver. Chem Biol Interact. 1992 Sep 14;84(1):55-68. The presence of the redox-cycling agent diquat in the perfusate (200 microM) increased the basal efflux of into bile (2.65 +/- 0.26 nmol GSH-equivalents/min per g liver wt.) and perfusate (0.55 +/- 0.15 nmol/min per g) approximately 10-fold. Only minor liver injury (release of lactate dehydrogenase activity) was observed. |
formation in isolated perfused rat 1(0,0,0,1) | Details |