Protein Information

Name glucose 6 phosphate dehydrogenase
Synonyms 6 phosphogluconolactonase; GDH; G6PDH; Glucose 6 phosphate dehydrogenase; GDH/6PGL endoplasmic bifunctional protein; GDH/6PGL endoplasmic bifunctional protein precursor; Glucose 1 dehydrogenase; Glucose dehydrogenase…

Compound Information

Name diquat
CAS

Reference List

PubMed Abstract RScore(About this table)
8934631 Cramer CT, Cooke S, Ginsberg LC, Kletzien RF, Stapleton SR, Ulrich RG: Upregulation of glucose-6-phosphate dehydrogenase in response to hepatocellular oxidative stress: studies with diquat. J Biochem Toxicol. 1995 Dec;10(6):293-8.

The ability of diquat, a compound known to enhance oxidative stress through generation of reactive oxygen species, to modulate the expression of G6PDH in primary cultures of Fischer-rat hepatocytes was examined.
139(1,2,6,9) Details
11814326 Slaughter MR, Thakkar H, O'Brien PJ: Effect of diquat on the antioxidant system and cell growth in human neuroblastoma cells. Toxicol Appl Pharmacol. 2002 Jan 15;178(2):63-70.

Viable cells were assayed for glutathione (GSH) and activities of catalase (CAT), superoxide dismutase (SOD), glutathione reductase (GR), glutathione peroxidase (GPX), and glucose-6-phosphate dehydrogenase (GPDH).
1(0,0,0,1) Details