Name | AHAS |
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Synonyms | 209L8; AHAS; Acetolactate synthase; Acetolactate synthase homolog; ILV2H; ILVB like; ILVBL; IlvB (Bacterial acetolactate synthase) like isoform 1 variant… |
Name | chlorimuron |
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CAS | 2-[[[[(4-chloro-6-methoxy-2-pyrimidinyl)amino]carbonyl]amino]sulfonyl]benzoic acid |
PubMed | Abstract | RScore(About this table) | |
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12496246 | Pang SS, Guddat LW, Duggleby RG: Molecular basis of sulfonylurea herbicide inhibition of acetohydroxyacid synthase. J Biol Chem. 2003 Feb 28;278(9):7639-44. Epub 2002 Dec 20. Here we report the 2.8 A resolution crystal structure of yeast AHAS in complex with a sulfonylurea herbicide, chlorimuron ethyl. |
82(1,1,1,2) | Details |
16127072 | Boigegrain RA, Liautard JP, Kohler S: Targeting of the virulence factor acetohydroxyacid synthase by sulfonylureas results in inhibition of intramacrophagic multiplication of Brucella suis. Antimicrob Agents Chemother. 2005 Sep;49(9):3922-5. The acetohydroxyacid synthase (AHAS) of Brucella suis can be effectively targeted by the sulfonylureas chlorimuron ethyl and metsulfuron methyl. |
82(1,1,1,2) | Details |
14684914 | Pang SS, Guddat LW, Duggleby RG: Crystallization of Arabidopsis thaliana acetohydroxyacid synthase in complex with the sulfonylurea herbicide chlorimuron ethyl. Acta Crystallogr D Biol Crystallogr. 2004 Jan;60(Pt 1):153-5. Epub 2003 Dec 18. Here, the crystallization and preliminary X-ray diffraction analysis of the catalytic subunit of Arabidopsis thaliana AHAS in complex with the sulfonylurea herbicide chlorimuron ethyl are reported. |
82(1,1,1,2) | Details |
9794808 | Hill CM, Duggleby RG: Mutagenesis of Escherichia coli acetohydroxyacid synthase isoenzyme II and characterization of three herbicide-insensitive forms. Biochem J. 1998 Nov 1;335 ( Pt 3):653-61. A plasmid containing the large and small subunit genes of AHAS II was mutagenized using and clones resistant to the sulphonylurea chlorimuron ethyl were selected. |
9(0,0,1,4) | Details |
15709745 | McCourt JA, Pang SS, Guddat LW, Duggleby RG: Elucidating the specificity of binding of sulfonylurea herbicides to acetohydroxyacid synthase. Biochemistry. 2005 Feb 22;44(7):2330-8. Acetohydroxyacid synthase (AHAS, EC 2.2.1.6) is the target for the sulfonylurea herbicides, which act as potent inhibitors of the enzyme. |
4(0,0,0,4) | Details |