| Name | aldehyde dehydrogenase (protein family or complex) |
|---|---|
| Synonyms | aldehyde dehydrogenase; aldehyde dehydrogenases |
| Name | calcium cyanamide |
|---|---|
| CAS | cyanamide calcium salt (1:1) |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 6861004 | Loomis CW, Brien JF: Specificity of hepatic aldehyde dehydrogenase inhibition by carbimide (calcium cyanamide) in the rat. Can J Physiol Pharmacol. 1983 Apr;61(4):431-5. |
163(2,2,2,3) | Details |
| 6640426 | Loomis CW, Brien JF: Inhibition of hepatic aldehyde dehydrogenases in the rat by carbimide (calcium cyanamide). Can J Physiol Pharmacol. 1983 Sep;61(9):1025-34. Oral administration of 7.0 mg/kg carbimide (calcium cyanamide, CC) to the rat produced differential inhibition of hepatic aldehyde dehydrogenase (ALDH) isozymes, as indicated by the time-course profiles of enzyme activity. |
112(1,2,2,2) | Details |
| 6733600 | Loomis CW, Brien JF: Decrease in carbimide (calcium cyanamide)-induced inhibition of rat hepatic aldehyde dehydrogenases by multiple administration. Can J Physiol Pharmacol. 1984 May;62(5):544-50. |
84(1,1,1,4) | Details |
| 3593530 | Kitson TM: The effect of cephalosporin antibiotics on metabolism: a review. Alcohol. 1987 May-Jun;4(3):143-8. The first of these is a potent inactivator of cytoplasmic aldehyde dehydrogenase only, the second affects both cytoplasmic and mitochondrial isoenzymes. 1-Methyltetrazole-5-thiol or derivatives have the potential to be used therapeutically as 'anti- compounds in the same way as disulfiram (Antabuse) or calcium cyanamide. |
32(0,1,1,2) | Details |
| 7232463 | Sinclair JD, Lindros KO: Suppression of drinking with brain aldehyde dehydrogenase inhibition. Pharmacol Biochem Behav. 1981 Mar;14(3):377-83. Calcium cyanamide, an aldehyde dehydrogenase (ALDH) inhibitor used in the treatment of alcoholism, strongly suppressed voluntary drinking by rats. |
32(0,1,1,2) | Details |
| 564706 | Tottmar O, Marchner H, Karlsson N: The presence of an aldehyde dehydrogenase inhibitor in animal diets and its effects on the experimental results in studies. Br J Nutr. 1978 Mar;39(2):317-24. The effects of chronic administration on the metabolism of and were studied in rats fed on a commercial diet containing an aldehyde dehydrogenase inhibitor, calcium cyanamide carbimide), as a contaminant in the calcinated bone-meal fraction of the diet. 2. |
32(0,1,1,2) | Details |
| 4041987 | Brien JF, Tam GS, Cameron RJ, Steenaart NA, Loomis CW: A comparative study of the inhibition of hepatic aldehyde dehydrogenases in the rat by methyltetrazolethiol, carbimide, and disulfiram. Can J Physiol Pharmacol. 1985 May;63(5):438-43. The time course of MTT-induced inhibition of hepatic aldehyde dehydrogenases (ALDH) was determined in adult, male Sprague-Dawley rats in comparison with the hepatic ALDH inhibition induced by carbimide (calcium cyanamide, CC) and disulfiram (D). |
32(0,1,1,2) | Details |
| 2764709 | Vasiliou V, Marselos M: Changes in the inducibility of a hepatic aldehyde dehydrogenase by various effectors. Arch Toxicol. 1989;63(3):221-5. A hepatic soluble aldehyde dehydrogenase (ALDH), inducible by polycyclic aromatic hydrocarbons, was studied in Wistar rats in connection with substances known to affect drug metabolism or aldehyde dehydrogenase activity, such as phenobarbital (PB), disulfiram (DS), beta-diethylaminoethyl diphenylpropylacetate (SKF 525A) and calcium cyanamide (CC). 3-Methylcholanthrene (MC) was given as a model inducer of ALDH (100 mg/kg, i.p., as a single dose) and the animals were killed after 3 days. |
32(0,1,1,2) | Details |
| 6353979 | Kupari M, Lindros K, Hillbom M, Heikkila J, Ylikahri R: Cardiovascular effects of accumulation after ingestion: their modification by beta-adrenergic blockade and alcohol dehydrogenase inhibition. Alcohol Clin Exp Res. 1983 Summer;7(3):283-8. Left ventricular function was examined by echocardiography and systolic time intervals in nine healthy male volunteers, who ingested 0.35 g/kg 4 hr after a 50-mg peroral dose of calcium cyanamide, an aldehyde dehydrogenase inhibitor. |
31(0,1,1,1) | Details |