| Name | tumor necrosis factor |
|---|---|
| Synonyms | Cachectin; DIF; TNF; TNF alpha; TNF a; TNFA; TNFSF 2; TNFSF2… |
| Name | cyanamide |
|---|---|
| CAS | cyanamide |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 12394292 | Kumar V, Silvis C, Nystrom G, Deshpande N, Vary TC, Frost RA, Lang CH: -induced increases in insulin-like growth factor binding protein-1 are partially mediated by TNF. Alcohol Clin Exp Res. 2002 Oct;26(10):1574-83. Separate groups of rats were also pretreated with 4-methylpyrazole (4-MP; alcohol dehydrogenase inhibitor), cyanamide (inhibitor of metabolism), RU486 (glucocorticoid receptor antagonist) or the tumor necrosis factor (TNF) antagonist (TNF (BP)) prior to EtOH administration. Separate groups of rats were also pretreated with 4-methylpyrazole (4-MP; alcohol dehydrogenase inhibitor), cyanamide (inhibitor of metabolism), RU486 (glucocorticoid receptor antagonist) or the tumor necrosis factor (TNF) antagonist (TNF (BP)) prior to EtOH administration. |
1(0,0,0,1) | Details |
| 15069620 | Nakamura Y, Yokoyama H, Higuchi S, Hara S, Kato S, Ishii H: accumulation suppresses Kupffer cell release of TNF-Alpha and modifies acute hepatic inflammation in rats. J Gastroenterol. 2004;39(2):140-7. This study was designed to clarify the role of in liver injury, specifically in vivo and in vitro effects on Kupffer cell release of the inflammatory cytokine tumor necrosis factor-alpha (TNF-Alpha). Similarly, isolated rat Kupffer cells were pretreated with disulfiram or cyanamide incubated in (1 h), then challenged with LPS and evaluated 2 h later for TNF-Alpha and levels in the culture medium. |
1(0,0,0,1) | Details |