| Name | superoxide dismutase |
|---|---|
| Synonyms | IPO B; Indophenoloxidase B; MNSOD; Manganese superoxide dismutase; Manganese containing superoxide dismutase; Mangano superoxide dismutase; Mn superoxide dismutase; Mn SOD… |
| Name | cyanamide |
|---|---|
| CAS | cyanamide |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 1961756 | Murphy ME, Sies H: Reversible conversion of anion to by superoxide dismutase. Proc Natl Acad Sci U S A. 1991 Dec 1;88(23):10860-4. When cyanamide and catalase were used to generate NO- in the presence of SOD, NO was measured by the conversion of HbO2 to MetHb. |
2(0,0,0,2) | Details |
| 3508430 | Younes M, Strubelt O: -induced hepatotoxicity: a role for free radicals. Free Radic Res Commun. 1987;3(1-5):19-26. Inhibition of alcohol dehydrogenase by 4-methylpyrazole or of aldehyde dehydrogenase by cyanamide totally abolished hepatotoxicity despite of a severalfold increase in concentration in the perfusate. Addition of superoxide dismutase or catalase clearly suppressed the -induced release of GPT and SDH, suggesting that .O2- and H2O2 are involved in this process. |
1(0,0,0,1) | Details |
| 8394073 | Mattia CJ, Adams JD Jr, Bondy SC: Free radical induction in the brain and liver by products of toluene catabolism. Biochem Pharmacol. 1993 Jul 6;46(1):103-10. Incubation of benzaldehyde with aldehyde dehydrogenase produced a strong signal that was blocked completely by superoxide dismutase and inhibited partially by catalase, suggesting the presence of radicals and the involvement of the iron-catalyzed Haber-Weiss reaction leading to the production of Pretreatment of rats in vivo with 4-methylpyrazole, an alcohol dehydrogenase inhibitor, or cyanamide, an aldehyde dehydrogenase inhibitor, prior to exposure to toluene, caused a significant decrease and increase, respectively, in toluene-stimulated rates of ROS generation in the CNS and liver. |
1(0,0,0,1) | Details |
| 10424762 | Clement B, Boucher JL, Mansuy D, Harsdorf A: Microsomal formation of and cyanamides from non-physiological N-hydroxyguanidines: N-hydroxydebrisoquine as a model substrate. Biochem Pharmacol. 1999 Aug 1;58(3):439-45. The oxidation of N-hydroxydebrisoquine by liver microsomes from rats pretreated with dexamethasone not only produced and the urea, but also the cyanamide derivative as the main metabolite. Experiments with catalase, superoxide dismutase, and H2O2 showed that the O2- formed from the enzyme and the substrate apparently participated in the reaction. |
1(0,0,0,1) | Details |
| 9860831 | Jousserandot A, Boucher JL, Henry Y, Niklaus B, Clement B, Mansuy D: Microsomal cytochrome P450 dependent oxidation of N-hydroxyguanidines, amidoximes, and ketoximes: mechanism of the oxidative cleavage of their C=N (OH) bond with formation of oxides. Biochemistry. 1998 Dec 8;37(49):17179-91. Oxidation of N-(4-chlorophenyl)-N'-- led to the formation of the corresponding urea and cyanamide in addition to NO, NO2-, and NO3-. |
0(0,0,0,0) | Details |