| Name | glutathione dependent formaldehyde dehydrogenase |
|---|---|
| Synonyms | ADH 3; ADH 5; ADH5; ADH5 protein; ADHX; Alcohol dehydrogenase 5; Alcohol dehydrogenase class 3 chi chain; Alcohol dehydrogenase class III chi chain… |
| Name | cyanamide |
|---|---|
| CAS | cyanamide |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 3089300 | Dicker E, Cederbaum AI: Inhibition of CO2 production from aminopyrine or by cyanamide or crotonaldehyde and the role of mitochondrial aldehyde dehydrogenase in oxidation. Biochim Biophys Acta. 1986 Aug 6;883(1):91-7. The partial sensitivity of CO2 production to inhibition by cyanamide or crotonaldehyde suggests that both the mitochondrial aldehyde dehydrogenase and formaldehyde dehydrogenase contribute towards the metabolism of which is generated from mixed-function oxidase activity or from just as both enzyme systems contribute towards the metabolism of exogenously added |
31(0,1,1,1) | Details |
| 3827870 | Dicker E, Cederbaum AI: Inhibition of the low-Km mitochondrial aldehyde dehydrogenase by diethyl and phorone in vivo and in vitro. Biochem J. 1986 Dec 15;240(3):821-7. The production of CO2 plus from 0.2 mM-[14C] by isolated hepatocytes was only slightly inhibited (15-30%) by incubation with diethyl or addition of cyanamide, suggesting oxidation primarily via formaldehyde dehydrogenase. |
83(1,1,1,3) | Details |
| 6742849 | Dicker E, Cederbaum AI: Effect of and cyanamide on the metabolism of by hepatocytes, mitochondria, and soluble supernatant from rat liver. Arch Biochem Biophys. 1984 Jul;232(1):179-88. These results suggest that, in rat hepatocytes, is oxidized by cyanamide- and -sensitive (low-Km aldehyde dehydrogenase) and insensitive (formaldehyde dehydrogenase) reactions, and that both enzymes appear to contribute about equally toward the overall metabolism of |
32(0,1,1,2) | Details |
| 6486817 | Dicker E, Cederbaum AI: Inhibition of the oxidation of and by hepatocytes and mitochondria by crotonaldehyde. Arch Biochem Biophys. 1984 Oct;234(1):187-96. In hepatocytes, crotonaldehyde produced about 30 to 40% inhibition of oxidation, which was similar to the inhibition produced by cyanamide. was a substrate for the low-Km mitochondrial aldehyde dehydrogenase, as well as for a cytosolic, glutathione-dependent formaldehyde dehydrogenase. |
2(0,0,0,2) | Details |