| Name | phosphodiesterase |
|---|---|
| Synonyms | CAMP specific phosphodiesterase variant PDE4A 10; CAMP specific phosphodiesterase variant TM3; CAMP specific phosphodiesterase; Cyclic AMP phosphodiesterase PDE4A11; Cyclic AMP specific phosphodiesterase HSPDE4A10; DPDE 2; DPDE2; PDE 4… |
| Name | cyanamide |
|---|---|
| CAS | cyanamide |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 15780613 | Deaton DN, Hassell AM, McFadyen RB, Miller AB, Miller LR, Shewchuk LM, Tavares FX, Willard DH Jr, Wright LL: Novel and potent cyclic cyanamide-based cathepsin K inhibitors. . Bioorg Med Chem Lett. 2005 Apr 1;15(7):1815-9. Starting from a PDE IV inhibitor hit derived from high throughput screening of the compound collection, a key pyrrolidine cyanamide pharmacophore was identified. |
31(0,1,1,1) | Details |
| 599570 | Sherwood E, Joshi A, Oro J: Cyanamide mediated syntheses under plausible primitive earth conditions. J Mol Evol. 1977 Dec 29;10(3):193-209. The di- and trinucleotide fractions were degraded 87% and 100% by snake venom phosphodiesterase and 39% and 9% by spleen phosphodiesterase. |
1(0,0,0,1) | Details |