Name | aldehyde oxidase |
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Synonyms | AO; AOH 1; AOH1; AOX 1; AOX1; Aldehyde Oxidase; Aldehyde oxidase 1; Aldeyde oxidase… |
Name | cyanamide |
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CAS | cyanamide |
PubMed | Abstract | RScore(About this table) | |
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3966800 | Svanas GW, Weiner H: Aldehyde dehydrogenase activity as the rate-limiting factor for metabolism in rat liver. Arch Biochem Biophys. 1985 Jan;236(1):36-46. To confirm that ALDH activity was the rate-limiting factor, low-Km ALDH in slices or intact mitochondria was partially inhibited by treatment with cyanamide and the rate of metabolism measured. A possible contribution by aldehyde oxidase was ruled out through the use of a competitive inhibitor, quinacrine. |
1(0,0,0,1) | Details |
2996550 | Kohn FR, Sladek NE: Aldehyde dehydrogenase activity as the basis for the relative insensitivity of murine pluripotent hematopoietic stem cells to oxazaphosphorines. Biochem Pharmacol. 1985 Oct 1;34(19):3465-71. The ex vivo sensitivity of murine pluripotent hematopoietic stem cells (CFU-S) and myeloid progenitor cells (CFU-GM) to 4-hydroperoxycyclophosphamide, ASTA Z 7557, phosphoramide mustard, acrolein, melphalan, and cis-platinum was determined in the absence and presence of known (disulfiram, diethyldithiocarbamate, cyanamide) or suspected [ethylphenyl (2-formylethyl) inhibitors of aldehyde dehydrogenase activity. |
0(0,0,0,0) | Details |
3978623 | Sladek NE, Landkamer GJ: Restoration of sensitivity to oxazaphosphorines by inhibitors of aldehyde dehydrogenase activity in cultured oxazaphosphorine-resistant L1210 and cross-linking agent-resistant P388 cell lines. Cancer Res. 1985 Apr;45(4):1549-55. The sensitivity of cultured L1210 and P388 cells sensitive (L1210/0, P388/0) and resistant (L1210/OAP, P388/CLA) to oxazaphosphorines, to 4-hydroperoxycyclophosphamide, ASTA Z-7557, phosphoramide mustard, and acrolein was determined in the absence and presence of known (disulfiram, diethyldithiocarbamate, cyanamide) or suspected [ethylphenyl (2-formylethyl) inhibitors of aldehyde dehydrogenase activity. |
0(0,0,0,0) | Details |