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Kumar V, Silvis C, Nystrom G, Deshpande N, Vary TC, Frost RA, Lang CH: Alcohol-induced increases in insulin-like growth factor binding protein-1 are partially mediated by TNF. Alcohol Clin Exp Res. 2002 Oct;26(10):1574-83.
Separate groups of rats were also pretreated with 4-methylpyrazole (4-MP; alcohol dehydrogenase inhibitor), cyanamide (inhibitor of acetaldehyde metabolism), RU486 (glucocorticoid receptor antagonist) or the tumor necrosis factor (TNF) antagonist (TNF (BP)) prior to EtOH administration.
Separate groups of rats were also pretreated with 4-methylpyrazole (4-MP; alcohol dehydrogenase inhibitor), cyanamide (inhibitor of acetaldehyde metabolism), RU486 (glucocorticoid receptor antagonist) or the tumor necrosis factor (TNF) antagonist (TNF (BP)) prior to EtOH administration. |
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