Protein Information

Name NF L
Synonyms 68 kDa neurofilament protein; CMT1F; CMT2E; NEFL; NF L; NF68; NFL; Neurofilament light polypeptide…

Compound Information

Name acrolein
CAS 2-propenal

Reference List

PubMed Abstract RScore(About this table)
8586023 He Y, Nagano M, Yamamoto H, Miyamoto E, Futatsuka M: Modifications of neurofilament proteins by possible metabolites of allyl chloride in vitro. Drug Chem Toxicol. 1995 Nov;18(4):315-31.

In relation to the mechanism (s), the present study was conducted to examine the abilities of ALL and its putative metabolites, i.e., epichlorohydrin, glycerol alpha-monochlorohydrin, allyl alcohol and acrolein to cross-link proteins in vitro.
1(0,0,0,1) Details
18823586 Jeong MS, Kang JH: Acrolein, the toxic endogenous aldehyde, induces neurofilament-L aggregation. BMB Rep. 2008 Sep 30;41(9):635-9.

In the present study, we examined the pattern of neurofilament-L (NF-L) modification elicited by acrolein.
417(5,5,7,7) Details