| Name | apolipoprotein |
|---|---|
| Synonyms | APOA 2; APOA2; APOAL; APOARGC; Apolipoprotein; Apolipoprotein (A) related gene C; Apolipoprotein (a); Apolipoprotein A II… |
| Name | acrolein |
|---|---|
| CAS | 2-propenal |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 16195596 | Arai H, Uchida K, Nakamura K: Effect of on acrolein modification of very low density lipoprotein and uptake of oxidized apolipoprotein e by hepatocytes. Biosci Biotechnol Biochem. 2005 Sep;69(9):1760-2. Acrolein modification of apolipoprotein (apo) E in human very low density lipoprotein (VLDL) was suppressed by |
81(1,1,1,1) | Details |
| 7583533 | McCall MR, Tang JY, Bielicki JK, Forte TM: Inhibition of lecithin-cholesterol acyltransferase and modification of HDL apolipoproteins by aldehydes. Arterioscler Thromb Vasc Biol. 1995 Oct;15(10):1599-606. The alpha,beta-unsaturated aldehydes acrolein and HNE were fourfold to eightfold more effective cross-linkers of apolipoproteins A-I and A-II than the other aldehydes studied. |
10(0,0,1,5) | Details |
| 16527993 | Vindis C, Escargueil-Blanc I, Elbaz M, Marcheix B, Grazide MH, Uchida K, Salvayre R, Negre-Salvayre A: Desensitization of platelet-derived growth factor receptor-beta by oxidized lipids in vascular cells and atherosclerotic lesions: prevention by scavengers. Circ Res. 2006 Mar 31;98(6):785-92. Epub 2006 Mar 9. This inhibition was associated with formation of (4HNE)- and acrolein-PDGFRbeta adducts and was mimicked by preincubation of cells with 4HNE. These PDGFRbeta adducts were also detected in aortae of apolipoprotein-deficient mice and hypercholesterolemic rabbits and in human carotid plaques. |
1(0,0,0,1) | Details |
| 17580963 | Tamamizu-Kato S, Wong JY, Jairam V, Uchida K, Raussens V, Kato H, Ruysschaert JM, Narayanaswami V: Modification by acrolein, a component of tobacco smoke and age-related oxidative stress, mediates functional impairment of human apolipoprotein E. Biochemistry. 2007 Jul 17;46(28):8392-400. Epub 2007 Jun 20. However, little is known about the potential oxidative damage to apolipoprotein E (apoE), an exchangeable antiatherogenic apolipoprotein. |
1(0,0,0,1) | Details |
| 9632657 | Uchida K, Kanematsu M, Morimitsu Y, Osawa T, Noguchi N, Niki E: Acrolein is a product of lipid peroxidation reaction. J Biol Chem. 1998 Jun 26;273(26):16058-66. However, there have been few detailed insights into the chemical mechanism of derivatization of apolipoproteins during oxidation. |
1(0,0,0,1) | Details |