Protein Information

Name Fas Ligand
Synonyms APT1LG1; FAS; APTL; Apoptosis (APO 1) antigen ligand 1; Apoptosis antigen ligand; Apoptosis antigen ligand 1; CD178; CD178 antigen…

Compound Information

Name acrolein
CAS 2-propenal

Reference List

PubMed Abstract RScore(About this table)
17196791 Tanel A, Averill-Bates DA: P38 and ERK mitogen-activated protein kinases mediate acrolein-induced apoptosis in Chinese hamster ovary cells. Cell Signal. 2007 May;19(5):968-77. Epub 2006 Nov 25.

Finally, acrolein induced phosphorylation of the pro-apoptotic factor p53 which is responsible for transcription of pro-apoptotic factors such as Bax and Fas ligand.
81(1,1,1,1) Details