| PubMed |
Abstract |
RScore(About this table) |
| 18448814 |
Park YS, Taniguchi N: Acrolein induces inflammatory response underlying endothelial dysfunction: a risk factor for atherosclerosis. Ann N Y Acad Sci. 2008 Apr;1126:185-9.
Our study demonstrates that acrolein, a known toxin in tobacco smoke, elevates oxidative stress via inactivation of thioredoxin reductase and stimulates expression of cyclooxygenase-2 through activation of the protein kinase C, p38 mitogen-activated protein kinase, and cAMP response element-binding protein pathway in endothelial cells. |
81(1,1,1,1) |
Details |
| 19135121 |
Myers CR, Myers JM: The effects of acrolein on peroxiredoxins, thioredoxins, and thioredoxin reductase in human bronchial epithelial cells. Toxicology. 2009 Mar 4;257(1-2):95-104. Epub 2008 Dec 24.
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7(0,0,1,2) |
Details |
| 15652504 |
Park YS, Misonou Y, Fujiwara N, Takahashi M, Miyamoto Y, Koh YH, Suzuki K, Taniguchi N: Induction of thioredoxin reductase as an adaptive response to acrolein in human umbilical vein endothelial cells. Biochem Biophys Res Commun. 2005 Feb 25;327(4):1058-65.
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7(0,0,1,2) |
Details |
| 15388247 |
Yang X, Wu X, Choi YE, Kern JC, Kehrer JP: Effect of acrolein and glutathione depleting agents on thioredoxin. . Toxicology. 2004 Nov 15;204(2-3):209-18.
In addition to glutathione (GSH), thioredoxin (Trx) and thioredoxin reductase (TR) contain thiol groups and may react with electrophiles. |
1(0,0,0,1) |
Details |