| Name | HBE1 |
|---|---|
| Synonyms | Epsilon globin; HBE; HBE 1; HBE1; Hemoglobin epsilon 1; Hemoglobin epsilon chain; Hemoglobin subunit epsilon; Hemoglobin epsilon 1s… |
| Name | acrolein |
|---|---|
| CAS | 2-propenal |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 15650393 | Valacchi G, Pagnin E, Phung A, Nardini M, Schock BC, Cross CE, van der Vliet A: Inhibition of NFkappaB activation and IL-8 expression in human bronchial epithelial cells by acrolein. Antioxid Redox Signal. 2005 Jan-Feb;7(1-2):25-31. To investigate how acrolein affects respiratory tract cell activation, we exposed either primary (NHBE) or immortalized human bronchial epithelial cells (HBE1) to 0-25 microM acrolein, and determined effects on basal and tumor necrosis factor-alpha (TNFalpha)-induced production of the chemokine interleukin (IL)-8. |
162(2,2,2,2) | Details |
| 18048804 | Zhang H, Forman HJ: Acrolein induces heme oxygenase-1 through PKC-delta and PI3K in human bronchial epithelial cells. Am J Respir Cell Mol Biol. 2008 Apr;38(4):483-90. Epub 2007 Nov 29. In this investigation we studied HO-1 induction in response to acrolein and determined the signaling pathways involved in human bronchial epithelial cells (HBE1 cells). |
12(0,0,2,2) | Details |
| 11788155 | Nardini M, Finkelstein EI, Reddy S, Valacchi G, Traber M, Cross CE, van der Vliet A: Acrolein-induced cytotoxicity in cultured human bronchial epithelial cells. Toxicology. 2002 Jan 25;170(3):173-85. In this study, the mechanisms of acrolein-induced cytotoxicity in human bronchial epithelial cells (HBE1) and the modulating effects of antioxidants were examined. |
6(0,0,1,1) | Details |
| 19651797 | Zhang H, Forman HJ: Signaling pathways involved in phase II gene induction by alpha, beta-unsaturated aldehydes. Toxicol Ind Health. 2009 May-Jun;25(4-5):269-78. This study is designed to answer this question using human bronchial epithelial cells (HBE1 cells) as a model and screening with a variety of protein kinase inhibitors with varying degrees of specificity. Two electrophiles, (HNE) and acrolein, induced the expression of phase II genes (GCLC, GCLM, NQO1, NQO2, HO-1, and GSTM-1). |
1(0,0,0,1) | Details |