Protein Information

Name P35
Synonyms GCHFR; p35; GFRP; GTP cyclohydrolase 1 feedback regulatory protein; GTP cyclohydrolase I feedback regulator; GTP cyclohydrolase I feedback regulatory protein; HsT16933; GTP cyclohydrolase 1 feedback regulatory proteins…

Compound Information

Name acrolein
CAS 2-propenal

Reference List

PubMed Abstract RScore(About this table)
16849425 Komeima K, Rogers BS, Lu L, Campochiaro PA: Antioxidants reduce cone cell death in a model of retinitis pigmentosa. . Proc Natl Acad Sci U S A. 2006 Jul 25;103(30):11300-5. Epub 2006 Jul 18.

The staining for acrolein in remaining cones at P35 was eliminated in antioxidant-treated rd1 mice, confirming that the treatment markedly reduced oxidative damage in cones; this was accompanied by a 2-fold increase in cone cell density and a 50% increase in medium-wavelength cone opsin mRNA.
38(0,1,2,3) Details