Protein Information

Name cIAP1
Synonyms API 1; API1; Apoptosis inhibitor 1; BIRC 2; BIRC2; Baculoviral IAP repeat containing protein 2; C IAP1; HIAP 2…

Compound Information

Name acrolein
CAS 2-propenal

Reference List

PubMed Abstract RScore(About this table)
19596284 Roy J, Pallepati P, Bettaieb A, Tanel A, Averill-Bates DA: Acrolein induces a cellular stress response and triggers mitochondrial apoptosis in A549 cells. Chem Biol Interact. 2009 Oct 7;181(2):154-67. Epub 2009 Jul 9.

Exposure to acrolein (<15microM, 30min) activated the survival factor AKT, which led to phosphorylation of Bad and induction of antiapoptosis proteins cIAP1/2.
81(1,1,1,1) Details