| Name | glucose 6 phosphate dehydrogenase |
|---|---|
| Synonyms | 6 phosphogluconolactonase; GDH; G6PDH; Glucose 6 phosphate dehydrogenase; GDH/6PGL endoplasmic bifunctional protein; GDH/6PGL endoplasmic bifunctional protein precursor; Glucose 1 dehydrogenase; Glucose dehydrogenase… |
| Name | acrolein |
|---|---|
| CAS | 2-propenal |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 8212054 | Trieff NM, Ficklen D, Gan J: In vitro inactivation of glucose-6-phosphate dehydrogenase from human red blood cells by acrolein: a possible biomarker of exposure. Toxicol Lett. 1993 Aug;69(2):121-7. |
37(0,1,2,2) | Details |
| 7728738 | Subramaniam S, Subramaniam S, Shyamala Devi CS: Erythrocyte antioxidant enzyme activity in CMF treated breast cancer patients. Cancer Biochem Biophys. 1994 Oct;14(3):177-82. Acrolein and phosphoramide mustard are the metabolites of cyclophosphamide which are among the causative agents which reduce the activity of dismultase, catalase, peroxidase, glutathione reductase, glutathione-S-transferase and glucose-6-phosphate dehydrogenase in erythrocytes of CMF treated breast cancer patients. |
31(0,1,1,1) | Details |
| 18501200 | Ansari MA, Roberts KN, Scheff SW: Oxidative stress and modification of synaptic proteins in hippocampus after traumatic brain injury. Free Radic Biol Med. 2008 Aug 15;45(4):443-52. Epub 2008 May 3. At various times post-TBI, animals were killed and the hippocampus was analyzed for antioxidants (GSH, peroxidase, glutathione reductase, glutathione-S-transferase, glucose-6-phosphate dehydrogenase, superoxide dismutase, and catalase) and oxidants (acrolein, protein carbonyl, and |
6(0,0,1,1) | Details |
| 12921788 | Al-Maghrebi MA, Al-Mulla F, Benov LT: induces apoptosis in a human breast cancer cell line. Arch Biochem Biophys. 2003 Sep 1;417(1):123-7. Activated phagocytes employ myeloperoxidase to generate and acrolein. Using breast cancer cells, we demonstrate that inactivates glucose-6-phosphate dehydrogenase, glyceraldehyde-3-phosphate dehydrogenase, and Cu,Zn superoxide dismutase, suppresses cell growth, and induces apoptosis. |
1(0,0,0,1) | Details |
| 4029094 | Patel JM, Block ER: Cyclophosphamide-induced depression of the antioxidant defense mechanisms of the lung. Exp Lung Res. 1985;8(2-3):153-65. We hypothesized that cyclophosphamide or one of its toxic metabolites, acrolein, may potentiate O2 toxicity by depressing lung antioxidant defense mechanisms. Excised lungs were analyzed for (GSH) content, glucose-6-phosphate dehydrogenase (G6PD), glutathione reductase (GSH-R), peroxidase (GSH-P), and superoxide dismutase (SOD) activities. |
1(0,0,0,1) | Details |
| 3862614 | Green GM: Mechanisms of tobacco smoke toxicity on pulmonary macrophage cells. Eur J Respir Dis Suppl. 1985;139:82-5. The filtered gas phase of cigarette smoke or acrolein suppresses phagocytic uptake and intracellular digestion of staphylococci when exposed in vitro; produces marked morphologic changes in the cytoplasmic membrane; inhibits cellular adhesion; disturbs glycolysis and arachidonic metabolism; inhibits and ATPase, glyceraldehyde 3-phosphate dehydrogenase, and probably endoperoxide E-isomerase, but not and ATPase, glucose 6-phosphate dehydrogenase or lactic dehydrogenase in a dose-response fashion. |
0(0,0,0,0) | Details |