Name | H2AX |
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Synonyms | H2A.X; H2A/X; H2AFX; H2AX; H2AX histone; Histone H2A.x; gamma H2AX; H2AX histones… |
Name | acrolein |
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CAS | 2-propenal |
PubMed | Abstract | RScore(About this table) | |
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18381427 | Wei G, DeFeo K, Hayes CS, Woster PM, Mandik-Nayak L, Gilmour SK: Elevated ornithine decarboxylase levels activate ataxia telangiectasia mutated-DNA damage signaling in normal keratinocytes. Cancer Res. 2008 Apr 1;68(7):2214-22. Ker/ODC also displays increased generation of H (2) O (2), acrolein- conjugates, and protein oxidation products as well as polyamine-dependent DNA damage, as measured by the comet assay and the expression of the phosphorylated form of the histone variant gamma H2AX. |
81(1,1,1,1) | Details |
18096571 | Malmlof M, Paajarvi G, Hogberg J, Stenius U: Mdm2 as a sensitive and mechanistically informative marker for genotoxicity induced by benzo [a] pyrene and dibenzo [a,l] pyrene. Toxicol Sci. 2008 Apr;102(2):232-40. Epub 2007 Dec 20. Acrolein potentiated the effect of BP on p53 stabilization and chromatin binding. |
0(0,0,0,0) | Details |