Protein Information

Name phosphodiesterase
Synonyms CAMP specific phosphodiesterase variant PDE4A 10; CAMP specific phosphodiesterase variant TM3; CAMP specific phosphodiesterase; Cyclic AMP phosphodiesterase PDE4A11; Cyclic AMP specific phosphodiesterase HSPDE4A10; DPDE 2; DPDE2; PDE 4…

Compound Information

Name acrolein
CAS 2-propenal

Reference List

PubMed Abstract RScore(About this table)
19080078 Wang X, Li JQ, Chen L, Wang HX, Sun BB, Wang T, Xu D, Wen FQ: [Effects of phosphodiesterase-4 inhibitor on the mucin secretion in airway stimulated with acrolein: experiment with rats]. Zhonghua Yi Xue Za Zhi. 2008 Nov 18;88(42):2988-93.
62(0,2,2,2) Details
3370625 Smith RA, Sysel IA, Tibbels TS, Cohen SM: Implications for the formation of abasic sites following modification of polydeoxycytidylic acid by acrolein in vitro. Cancer Lett. 1988 May;40(1):103-9.

Separate aliquots of the reaction mixture were digested to deoxynucleotide 3'-monophosphates by incubation with micrococcal nuclease and spleen phosphodiesterase.
1(0,0,0,1) Details
19129291 Wang T, Liu Y, Chen L, Wang X, Hu XR, Feng YL, Liu DS, Xu D, Duan YP, Lin J, Ou XM, Wen FQ: Effect of sildenafil on acrolein-induced airway inflammation and mucus production in rats. Eur Respir J. 2009 May;33(5):1122-32. Epub 2009 Jan 7.

Phosphodiesterase (PDE) inhibitors have shown anti-inflammatory properties.
1(0,0,0,1) Details