| Name | carbonic anhydrases (protein family or complex) |
|---|---|
| Synonyms | carbonic anhydrase; carbonic anhydrases |
| Name | acrolein |
|---|---|
| CAS | 2-propenal |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 2501305 | Tu C, Wynns GC, Silverman DN: Chemical modification of carbonic anhydrase II with acrolein. . J Biol Chem. 1989 Jul 25;264(21):12389-93. The catalyzed rate of interconversion of CO2 and HCO3- at chemical equilibrium was the same for the acrolein-modified and the unmodified carbonic anhydrases, but the rate of release of 18O-labeled water from the active site had decreased by as much as 85% for the acrolein-modified enzyme. |
81(1,1,1,1) | Details |
| 9692974 | Earnhardt JN, Qian M, Tu C, Lakkis MM, Bergenhem NC, Laipis PJ, Tashian RE, Silverman DN: The catalytic properties of murine carbonic anhydrase VII. Biochemistry. 1998 Jul 28;37(30):10837-45. Carbonic anhydrase VII (CA VII) appears to be the most highly conserved of the active mammalian carbonic anhydrases. The magnitude of Kcat, its pH profile, 18O-exchange data for both wild-type and a H64A mutant, and inhibition by CuSO4 and acrolein suggest that the at position 64 is functioning as a -transfer group and is responsible for one of the observed ionizations. |
1(0,0,0,1) | Details |