Protein Information

Name ADAM17
Synonyms A disintegrin and metalloproteinase domain 17; ADAM 17; ADAM 17 precursor; ADAM17; ADAM17 protein; CD156B; CD156b antigen; CSVP…

Compound Information

Name acrolein
CAS 2-propenal

Reference List

PubMed Abstract RScore(About this table)
15531749 Deshmukh HS, Case LM, Wesselkamper SC, Borchers MT, Martin LD, Shertzer HG, Nadel JA, Leikauf GD: Metalloproteinases mediate mucin 5AC expression by epidermal growth factor receptor activation. Am J Respir Crit Care Med. 2005 Feb 15;171(4):305-14. Epub 2004 Nov 5.

Small, interfering RNA directed against ADAM17 or MMP9 inhibited the acrolein-induced MUC5AC mRNA increase.
193(2,3,3,3) Details