| Name | eIF 2alpha |
|---|---|
| Synonyms | EIF 2; EIF 2A; EIF2A; EIF 2alpha; EIF2; EIF2 alpha; EIF2S1; Eukaryotic translation initiation factor 2 alpha… |
| Name | acrolein |
|---|---|
| CAS | 2-propenal |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 19041636 | Keith RJ, Haberzettl P, Vladykovskaya E, Hill BG, Kaiserova K, Srivastava S, Barski O, Bhatnagar A: Aldose reductase decreases endoplasmic reticulum stress in ischemic hearts. Chem Biol Interact. 2009 Mar 16;178(1-3):242-9. Epub 2008 Nov 11. In cell culture experiments, exposure to model lipid peroxidation aldehydes-4-hydroxy-trans-2-nonenal (HNE), 1-palmitoyl-2-oxovaleroyl (POVPC) or acrolein led to an increase in the phosphorylation of ER stress markers PERK and eIF2-alpha and an increase in ATF3. |
83(1,1,1,3) | Details |
| 18951912 | Haberzettl P, Vladykovskaya E, Srivastava S, Bhatnagar A: Role of endoplasmic reticulum stress in acrolein-induced endothelial activation. Toxicol Appl Pharmacol. 2009 Jan 1;234(1):14-24. Epub 2008 Oct 7. Treatment of human umbilical vein endothelial cells (HUVECs) with 2 to 10 microM acrolein led to an increase in the phosphorylation of eIF-2alpha within 10 to 30 min of exposure. |
81(1,1,1,1) | Details |