| Name | caspase 3 |
|---|---|
| Synonyms | Apopain; CASP 3; CASP3; CPP 32; CPP32; CPP32B; Caspase 3; Caspase 3 precursor… |
| Name | sodium fluoride |
|---|---|
| CAS | sodium fluoride (NaF) |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 19009284 | Yan X, Feng C, Chen Q, Li W, Wang H, Lv L, Smith GW, Wang J: Effects of sodium fluoride treatment in vitro on cell proliferation, apoptosis and caspase-3 and caspase-9 mRNA expression by neonatal rat osteoblasts. Arch Toxicol. 2009 May;83(5):451-8. Epub 2008 Oct 21. |
13(0,0,2,3) | Details |
| 19852076 | Xu B, Xu Z, Xia T, He P, Gao P, He W, Zhang M, Guo L, Niu Q, Wang A: Effects of the Fas/Fas-L pathway on -induced apoptosis in SH-SY5Y cells. Environ Toxicol. 2009 Oct 22. To investigate apoptosis, caspase-3 activity, and mRNA expression of Fas, Fas-L, and caspases (-3 and -8) induced by human neuroblastoma (SH-SY5Y) cells were incubated with 0, 20, 40, and 80 mg/L sodium fluoride (NaF) for 24 h in vitro. |
7(0,0,1,2) | Details |
| 11461774 | Anuradha CD, Kanno S, Hirano S: Oxidative damage to mitochondria is a preliminary step to caspase-3 activation in -induced apoptosis in HL-60 cells. Free Radic Biol Med. 2001 Aug 1;31(3):367-73. |
3(0,0,0,3) | Details |
| 16136339 | Zhan XA, Wang M, Xu ZR, Li WF, Li JX: Evaluation of caspase-dependent apoptosis during -induced liver lesion in pigs. Arch Toxicol. 2006 Feb;80(2):74-80. Epub 2005 Sep 1. The obvious DNA ladder and the significantly increased both hepatic caspase-9 and caspase-3 activity indicated that induced caspase-dependent apoptosis in vivo. |
2(0,0,0,2) | Details |
| 15849362 | Kubota K, Lee DH, Tsuchiya M, Young CS, Everett ET, Martinez-Mier EA, Snead ML, Nguyen L, Urano F, Bartlett JD: induces endoplasmic reticulum stress in ameloblasts responsible for dental enamel formation. J Biol Chem. 2005 Jun 17;280(24):23194-202. Epub 2005 Apr 23. Analysis of control and GADD153 (-/-) embryonic fibroblasts demonstrated that caspase-3 mediated the increased DNA fragmentation observed in the GADD153 null cells. |
1(0,0,0,1) | Details |
| 19493891 | Karube H, Nishitai G, Inageda K, Kurosu H, Matsuoka M: NaF activates MAPKs and induces apoptosis in odontoblast-like cells. J Dent Res. 2009 May;88(5):461-5. MDPC-23 cells incubated with 5 mM NaF for 24 hrs exhibited caspase-3 activation, cleavage of poly (ADP- polymerase, DNA fragmentation, and an increase in cytoplasmic nucleosomes. |
1(0,0,0,1) | Details |
| 16433036 | Chien CH, Ali Chowdhury S, Sakagami H, Kanegae H: Enhancement of sodium fluoride-induced cell death by centrifugal force. In Vivo. 2006 Jan-Feb;20(1):103-8. The combination of NaF and centrifugal force enhanced caspase-3 activity. |
1(0,0,0,1) | Details |
| 16309196 | Takeuchi R, Hoshijima H, Onuki N, Nagasaka H, Chowdhury SA, Kawase M, Sakagami H: Effect of anticancer agents on codeinone-induced apoptosis in human cancer cell lines. Anticancer Res. 2005 Nov-Dec;25(6B):4037-41. Codeinone dose-dependently activated caspase-3 in both of these cells, but to a much lesser extent than that attained by actinomycin D. The cytotoxic activity of codeinone against HSC-2 cells was inhibited by N-acetyl- but somewhat additively stimulated by peroxide, sodium fluoride, 5-fluorouridine, cisplatin, doxorubicin and methotrexate. |
1(0,0,0,1) | Details |
| 14981920 | Morshed SR, Tokunaga T, Otsuki S, Takayama F, Satoh T, Hashimoto K, Yasui T, Okamura M, Shimada J, Kashimata M, Sakagami H: Effect of antitumor agents on cytotoxicity induction by sodium fluoride. . Anticancer Res. 2003 Nov-Dec;23(6C):4729-36. Most Group I compounds except doxorubicin (which induced DNA fragmentation less effectively than others) activated caspase 3 more efficiently than Group II compounds. |
1(0,0,0,1) | Details |
| 19322641 | Agarwal R, Mumtaz H, Ali N: Role of inositol polyphosphates in programmed cell death. Mol Cell Biochem. 2009 Aug;328(1-2):155-65. Epub 2009 Mar 26. Additionally, we measured changes in AKT phosphorylation, cleavage of caspase-3 and caspase-9, and release of cytochrome C from mitochondria into cytosol. |
1(0,0,0,1) | Details |
| 17203778 | Chien CH, Otsuki S, Chowdhury SA, Kobayashi M, Takahashi K, Kanda Y, Kunii S, Sakagami H, Kanegae H: Enhancement of cytotoxic activity of sodium fluoride against human periodontal ligament fibroblasts by water pressure. In Vivo. 2006 Nov-Dec;20(6B):849-56. |
0(0,0,0,0) | Details |
| 20044612 | Chu Q, Amano O, Kanda Y, Kunii S, Wang Q, Sakagami H: Tumor-specific cytotoxicity and type of cell death induced by gefitinib in oral squamous cell carcinoma cell lines. Anticancer Res. 2009 Dec;29(12):5023-31. Non-cytotoxic concentration of gefitinib effectively enhanced the cytotoxicity of docetaxel against HSC-2 and T98G cell, but failed to enhance the cytotoxicity of other antitumor agents (mitoxantrone, doxorubicin, methotrexate, cisplatin, sodium fluoride) or herbal extracts (Drynaria baronii, Angelica sinensis and Cornus officinalis Sieb. et Zucc). |
0(0,0,0,0) | Details |
| 19414411 | Chien CH, Sakagami H, Kouhara M, Sasaki A, Matsumoto K, Kanegae H: Effect of simulated orthodontic forces on -induced cytotoxicity in MC3T3-E1 osteoblast-like cells. In Vivo. 2009 Mar-Apr;23(2):259-65. The effects of simulated orthodontic forces such as centrifugal force or water pressure on sodium fluoride (NaF)-induced cytotoxicity against mouse osteoblast-like cells MC3T3-E1 were investigated. |
0(0,0,0,0) | Details |