Name | Acetylcholinesterase |
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Synonyms | ACHE; ACHE protein; AChE; ARACHE; AcChoEase; Acetylcholine acetylhydrolase; Acetylcholinesterase; Acetylcholinesterase isoform E4 E6 variant… |
Name | sodium fluoride |
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CAS | sodium fluoride (NaF) |
PubMed | Abstract | RScore(About this table) | |
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19635623 | Flora SJ, Mittal M, Mishra D: Co-exposure to arsenic and linked enzymes, biogenic amines and DNA damage in mouse brain. J Neurol Sci. 2009 Oct 15;285(1-2):198-205. Epub 2009 Jul 26. Male mice were exposed to meta arsenite (50 ppm) and sodium fluoride (50 ppm) individually and in combination for ten weeks. However; acetyl cholinesterase (AChE) and monoamine oxidase (MAO) activities showed an increase on exposure. |
on oxidative stress, 2(0,0,0,2) | Details |
11455057 | Sargento L, Sobral do Rosario H, Saldanha C, Martins-Silva J: Hemorheological effects of fluorescein in rats. Clin Hemorheol Microcirc. 2001;24(3):175-81. A blood sample was drawn by aortic puncture after 60 minutes and hemorheological parameters determined: hematocrit, hemoglobin, metahemoglobin, carboxyhemoglobin, plasma viscosity, erythrocyte deformability, membrane fluidity and acetylcholinesterase activity. |
2(0,0,0,2) | Details |
12071426 | Ekambaram P, Paul V: Modulation of toxicity in rats by and by withdrawal of exposure. Pharmacol Toxicol. 2002 Feb;90(2):53-8. In order to assess the effect of on the toxic effects of adult female Wistar rats were treated with sodium fluoride (NaF, 500 ppm in drinking water) alone or in combination with (CaCO3, 50 mg/ kg by oral intubation) daily for 60 days. Body weight gain, exploratory motor activity, rota-rod motor coordination, dental structure, activities of acetylcholinesterase (AchE, brain and skeletal muscle) and Na+ K+ ATPase (erythrocyte membrane and skeletal muscle) and the concentrations of protein (serum and skeletal muscle), (serum) and (serum) were determined in these animals 24 hr after the last treatment. |
1(0,0,0,1) | Details |
15080879 | Ceron JJ, Martinez-Subiela S, Hennemann C, Tecles F: The effects of different anticoagulants on routine canine plasma biochemistry. Vet J. 2004 May;167(3):294-301. The effects of ethylenediaminetetraacetic acid (EDTA), and sodium fluoride/ on plasma biochemistry results in dogs were studied and compared with serum. Differences in albumin, acetylcholinesterase, ionized and were found between serum and heparinized plasma. |
1(0,0,0,1) | Details |
17420053 | Coplan MJ, Patch SC, Masters RD, Bachman MS: Confirmation of and explanations for elevated blood lead and other disorders in children exposed to water disinfection and fluoridation chemicals. Neurotoxicology. 2007 Sep;28(5):1032-42. Epub 2007 Mar 1. Unlike the fully ionized state of (F-) in water treated with sodium fluoride (NaFW), the SiF anion, [SiF6] 2- in SiFW releases F- in a complicated dissociation process. A German PhD study found that SiFW is a more powerful inhibitor of acetylcholinesterase (AChE) than NaFW. |
1(0,0,0,1) | Details |
20303930 | Ashani Y, Gupta RD, Goldsmith M, Silman I, Sussman JL, Tawfik DS, Leader H: Stereo-specific synthesis of analogs of nerve agents and their utilization for selection and characterization of paraoxonase (PON1) catalytic scavengers. Chem Biol Interact. 2010 Mar 19. The configurational assignments of the S (P) and R (P) isomers, as well as their optical purity, were established by X-ray diffraction, reaction with sodium fluoride, hydrolysis by selected rePON1 variants, and inhibition of AChE. |
83(1,1,1,3) | Details |
9559097 | Zhao XL, Wu JH: Actions of sodium fluoride on acetylcholinesterase activities in rats. Biomed Environ Sci. 1998 Mar;11(1):1-6. |
15(0,0,2,5) | Details |
11292576 | Ekambaram P, Paul V: Spontaneous motor activity, rota-rod performance (motor co-ordination), body weight gain, food intake, activities of total cholinesterase (blood) and acetylcholinesterase (brain), and dental structure were determined in adult female rats treated with a very high dose of sodium fluoride (500 ppm in drinking water) alone and in combination with (50 mg/kg body weight by oral intubation) for 60 days. |
preventing locomotor behavioral and dental toxicities of by decreasing serum level in rats. Environ Toxicol Pharmacol. 2001 Mar;9(4):141-146.7(0,0,1,2) | Details |
18236229 | Dabisch PA, Davis EA, Renner JA, Jakubowski EM, Mioduszewski RJ, Thomson SA: Biomarkers of low-level exposure to soman vapor: comparison of acetylcholinesterase inhibition. Inhal Toxicol. 2008 Jan;20(2):149-56. |
regeneration to 4(0,0,0,4) | Details |