| Name | angiotensin II |
|---|---|
| Synonyms | AGT; ANG II; ANHU; Angiotensin I; Angiotensin II; Angiotensinogen; Angiotensinogen precursor; SERPINA 8… |
| Name | sodium fluoride |
|---|---|
| CAS | sodium fluoride (NaF) |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 9882708 | Ushio-Fukai M, Alexander RW, Akers M, Lyons PR, Lassegue B, Griendling KK: Angiotensin II receptor coupling to phospholipase D is mediated by the betagamma subunits of heterotrimeric G proteins in vascular smooth muscle cells. Mol Pharmacol. 1999 Jan;55(1):142-9. In intact cells, Ang II activation of PLD was pertussis toxin-insensitive and was not additive with sodium fluoride, a cell-permeant activator of heterotrimeric G proteins, indicating that AT1 receptor-PLD coupling requires pertussis toxin-insensitive heterotrimeric G proteins. |
7(0,0,0,7) | Details |
| 9648724 | Sayeski PP, Ali MS, Harp JB, Marrero MB, Bernstein KE: Phosphorylation of p130Cas by angiotensin II is dependent on c-Src, intracellular Ca2+, and protein kinase C. Circ Res. 1998 Jun 29;82(12):1279-88. |
7(0,0,0,7) | Details |
| 11108140 | Sayeski PP, Ali MS, Bernstein KE: The role of Ca2+ mobilization and heterotrimeric G protein activation in mediating phosphorylation signaling patterns in vascular smooth muscle cells. Mol Cell Biochem. 2000 Sep;212(1-2):91-8. This work investigated the role of Ca2+ mobilization and heterotrimeric G protein activation in mediating angiotensin II-dependent phosphorylation signaling patterns. |
6(0,0,0,6) | Details |
| 18971210 | Jensen AM, Bae EH, Fenton RA, Norregaard R, Nielsen S, Kim SW, Frokiaer J: Angiotensin II regulates V2 receptor and pAQP2 during ureteral obstruction. Am J Physiol Renal Physiol. 2009 Jan;296(1):F127-34. Epub 2008 Oct 29. Furthermore, cAMP generation in sodium fluoride- and forskolin-stimulated inner medullary membrane fractions was studied after release of BUO. |
3(0,0,0,3) | Details |
| 10608476 | Ge C, Garcia R, Anand-Srivastava MB: Altered expression of Gi-protein and adenylyl cyclase activity in hearts from one kidney one clip hypertensive rats: effect of captopril. J Hypertens. 1999 Nov;17(11):1617-26. OBJECTIVE: To investigate whether one kidney one clip (1K-1C) hypertensive rats associated with high levels of angiotensin II (Ang II) exhibit enhanced expression and functions of G proteins in the heart and whether the enhanced expression can be attributed to Ang II. 5'-[3'-thio] (GTPgammaS), isoproterenol, glucagon, sodium fluoride (NaF) and forskolin (FSK) stimulated adenylyl cyclase activity in hearts from control and hypertensive rats to varying degrees; however, the stimulations were significantly less in hypertensive rats compared with control rats. |
3(0,0,0,3) | Details |
| 11679958 | Schepke M, Heller J, Paschke S, Thomas J, Wolff M, Neef M, Malago M, Molderings GJ, Spengler U, Sauerbruch T: Contractile hyporesponsiveness of hepatic arteries in humans with cirrhosis: evidence for a receptor-specific mechanism. Hepatology. 2001 Nov;34(5):884-8. Therefore, we assessed the vascular response of human hepatic arteries after activating the G-protein-dependent signal transduction pathway by stimulation with angiotensin II, the A (2) analog U46619, or by G-protein activation with NaF/AlCl (3). |
3(0,0,0,3) | Details |
| 16998537 | Ge C, Garcia R, Anand-Srivastava MB: Enhanced expression of Gialpha protein and adenylyl cyclase signaling in aortas from 1 kidney 1 clip hypertensive rats. Can J Physiol Pharmacol. 2006 Jul;84(7):739-46. The increased expression of Gialpha and blood pressure was restored toward WKY levels by captopril treatment, suggesting a role for angiotensin (Ang) II in the enhanced expression of Gialpha protein and blood pressure. |
3(0,0,0,3) | Details |
| 8818336 | Dumont EC, Lambert C, Lamontagne D: Modification of aortic contractility in the cardiomyopathic hamster. Br J Pharmacol. 1996 Jul;118(5):1141-6. Dose-response curves to (1 nM-0.1 mM), angiotensin II (10 pM-0.3 microM), (1 nM-0.1 mM) and KCl (1 mM-0.1 M) were performed. |
2(0,0,0,2) | Details |
| 11900377 | Anand-Srivastava MB, Wang R, Liu YY: Alterations in g-protein-linked signal transduction in vascular smooth muscle in diabetes. Adv Exp Med Biol. 2001;498:263-71. On the other hand, the stimulatory effects of GTPgammaS, isoproterenol, glucagon, forskolin (FSK) and sodium fluoride on adenylyl cyclase were enhanced in STZ-rats. In addition, receptor-mediated inhibition of adenylyl cyclase by angiotensin II (AII), oxotremorine and atrial natriuretic peptide (ANP) was attenuated in STZ rats. |
1(0,0,0,1) | Details |
| 12054468 | Boumati M, Li Y, Anand-Srivastava MB: Modulation of ANP-C receptor signaling by endothelin-1 in A-10 smooth muscle cells. Arch Biochem Biophys. 2002 May 15;401(2):178-86. We have previously shown that pretreatment of A-10 smooth muscle cells (SMC) with angiotensin II (Ang II) attenuated atrial natriuretic peptide (ANP) receptor-C (ANP-C)-mediated inhibition of adenylyl cyclase without altering (125) I-ANP binding. |
1(0,0,0,1) | Details |
| 15306227 | Hashim S, Li Y, Nagakura A, Takeo S, Anand-Srivastava MB: Modulation of G-protein expression and adenylyl cyclase signaling by high in vascular smooth muscle. Cardiovasc Res. 2004 Sep 1;63(4):709-18. In addition, receptor-dependent and -independent functions of Gialpha proteins were attenuated in hyperglycemic cells, as demonstrated by inhibition of forskolin (FSK)-stimulated adenylyl cyclase activity by low concentration of GTPgammaS or by angiotensin II (Ang II), oxotremorine or C-ANP (4-23) (a ring deleted analog of atrial natriuretic peptide). On the other hand, the stimulatory effects of GTPgammaS, glucagon, isoproterenol, FSK and sodium fluoride on adenylyl cyclase were significantly augmented in hyperglycemic cells as compared to control cells, whereas basal adenylyl cyclase activity was significantly lower in hyperglycemic cells as compared to control cells. |
1(0,0,0,1) | Details |
| 15106810 | Hashim S, Anand-Srivastava MB: Losartan-induced attenuation of blood pressure in L-NAME hypertensive rats is associated with reversal of the enhanced expression of Gi alpha proteins. J Hypertens. 2004 Jan;22(1):181-90. In addition, the stimulatory effects of 5'-gamma-thiotriphosphate (GTPgammaS), isoproterenol, 5'-N-ethylcarboxamideadenosine (NECA), glucagon, forskolin (FSK) and sodium fluoride (NaF) on adenylyl cyclase, which were diminished in L-NAME-treated rats, were reversed by losartan treatment. In addition, losartan was able to reverse the attenuated receptor-mediated inhibitions of adenylyl cyclase by oxotremorine and angiotensin II towards control. |
1(0,0,0,1) | Details |
| 10677348 | Palaparti A, Li Y, Anand-Srivastava MB: Inhibition of atrial natriuretic peptide (ANP) C receptor expression by antisense oligodeoxynucleotides in A10 vascular smooth-muscle cells is associated with attenuation of ANP-C-receptor-mediated inhibition of adenylyl cyclase. Biochem J. 2000 Mar 1;346 Pt 2:313-20. In addition, the stimulatory effects of nucleotides, isoproterenol, sodium fluoride and forskolin as well as the inhibitory effects of angiotensin II on adenylyl cyclase were not affected by antisense-oligonucleotide treatment. |
0(0,0,0,0) | Details |