| Name | bradykinin |
|---|---|
| Synonyms | Alpha 2 thiol proteinase inhibitor; BDK; Bradykinin; KNG; KNG 1; KNG1; Kininogen; Kininogen 1 precursor… |
| Name | sodium fluoride |
|---|---|
| CAS | sodium fluoride (NaF) |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 10536676 | Perrault LP, Bidouard JP, Janiak P, Villeneuve N, Bruneval P, Vilaine JP, Vanhoutte PM: Impairment of G-protein-mediated signal transduction in the porcine coronary endothelium during rejection after heart transplantation. Cardiovasc Res. 1999 Aug 1;43(2):457-70. Endothelium-dependent relaxations to and to the alpha 2-adrenergic agonist UK14304 (which both activate receptors coupled to Gi-proteins) and to sodium fluoride (a direct activator of G-proteins) were decreased 30 days after transplantation, while those to the ionophore, A23187, and bradykinin were shifted to the right and those to ADP were normal. |
31(0,1,1,1) | Details |
| 10712398 | Perrault LP, Mahlberg F, Breugnot C, Bidouard JP, Villeneuve N, Vilaine JP, Vanhoutte PM: Hypercholesterolemia increases coronary endothelial dysfunction, lipid content, and accelerated atherosclerosis after heart transplantation. Arterioscler Thromb Vasc Biol. 2000 Mar;20(3):728-36. Endothelium-dependent relaxations to to the alpha (2)-adrenergic agonist UK14,304, and to the direct G-protein activator sodium fluoride were decreased significantly in allografted hearts compared with native hearts from both groups. Relaxations to the ionophore A23187 and bradykinin were decreased significantly in allografts from animals fed the high diet. |
1(0,0,0,1) | Details |
| 15273823 | Rodrigues AJ, Evora PR, Schaff HV: Protective effect of against radical-mediated coronary artery injury. Braz J Med Biol Res. 2004 Aug;37(8):1215-24. Epub 2004 Jul 20. Subsequently, concentration-response curves for ionophore and sodium fluoride were obtained in the presence of 20 microM indomethacin. Concentration-response curves for bradykinin, ionophore, sodium nitroprusside, and pinacidil were obtained in the presence of indomethacin plus Nomega-nitro- (0.2 mM). |
1(0,0,0,1) | Details |
| 9229295 | Perrault LP, Bidouard JP, Janiak P, Villeneuve N, Bruneval P, Vilaine JP, Vanhoutte PM: Time course of coronary endothelial dysfunction in acute untreated rejection after heterotopic heart transplantation. J Heart Lung Transplant. 1997 Jun;16(6):643-57. At 14 days maximal relaxations to the ionophore A23187, and bradykinin were also reduced, but to a lesser degree than those to and sodium fluoride. |
81(1,1,1,1) | Details |
| 11299208 | Thompson LP, Weiner CP: Pregnancy enhances G protein activation and release from uterine arteries. Am J Physiol Heart Circ Physiol. 2001 May;280(5):H2069-75. Relaxation and contraction to NaF (0.5-11.5 mM), (10 (-9)-10 (-5) M), and bradykinin (10 (-12)-3 x 10 (-5) M) were measured in isolated UA of pregnant and nonpregnant guinea pigs. |
3(0,0,0,3) | Details |
| 17903241 | Smith N, Browning CA, Duroudier N, Stewart C, Peel S, Swan C, Hall IP, Sayers I: Salmeterol and cytokines modulate signalling in human airway smooth muscle cells via regulation at the receptor locus. Respir Res. 2007 Sep 28;8:68. No treatment significantly influenced sodium fluoride induced IPx responses suggesting regulation occurs at the receptor locus. The effect of cytokine or asthma medication on or bradykinin induced IPx signalling was assessed by [3H] inositol incorporation. |
2(0,0,0,2) | Details |
| 11211191 | Demers P, Elkouri S, Sirois MG, Cartier R: Coronary artery endothelial dysfunction after ischemia-reperfusion and acute untreated rejection in a canine heterotopic heart transplantation model. Transplantation. 2001 Jan 15;71(1):26-32. Endothelium-dependent responses to ionophore A23147, and bradykinin were unaffected in groups 1 and 2. Endothelial relaxations to sodium fluoride (Gi-protein activator) was significantly reduced in group 1 and significantly increased in group 2 compared with control. |
1(0,0,0,1) | Details |
| 8769995 | Rosenstock M, Danon A, Rimon G: Dual regulation of PLA2 and production by G proteins in bovine aortic endothelial cells. Am J Physiol. 1996 Aug;271(2 Pt 1):C555-62. In addition, phenylisopropyl inhibited the release of AA and whereas ATP and bradykinin increased |
1(0,0,0,1) | Details |
| 9481676 | Graier WF, Paltauf-Doburzynska J, Hill BJ, Fleischhacker E, Hoebel BG, Kostner GM, Sturek M: Submaximal stimulation of porcine endothelial cells causes focal Ca2+ elevation beneath the cell membrane. J Physiol. 1998 Jan 1;506 ( Pt 1):109-25. Sodium fluoride (10 mmol l-1) and submaximal concentrations of bradykinin (Bk; 1 nmol l-1) stimulated Ca2+ entry with no increase in [Ca2+] b. |
0(0,0,0,0) | Details |