Protein Information

Name MKK6
Synonyms Dual specificity mitogen activated protein kinase kinase 6; MAP kinase kinase 6; MAP2K6; MAPK/ERK kinase 6; MAPKK 6; MAPKK6; MEK 6; MEK6…

Compound Information

Name sodium fluoride
CAS sodium fluoride (NaF)

Reference List

PubMed Abstract RScore(About this table)
16407301 Fritz A, Brayer KJ, McCormick N, Adams DG, Wadzinski BE, Vaillancourt RR: Phosphorylation of serine 526 is required for MEKK3 activity, and association with 14-3-3 blocks dephosphorylation. J Biol Chem. 2006 Mar 10;281(10):6236-45. Epub 2006 Jan 9.

In addition, phosphorylation of Ser526 was required for MKK6 phosphorylation in vitro, whereas dephosphorylation of Ser526 was mediated by protein phosphatase 2A and sensitive to okadaic acid and sodium fluoride.
31(0,1,1,1) Details