Name | caspase 9 |
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Synonyms | APAF 3; APAF3; Apoptotic protease MCH6; Apoptotic protease Mch 6; Apoptotic protease activating factor 3; CASP 9; CASP9; CASPASE 9c… |
Name | sodium fluoride |
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CAS | sodium fluoride (NaF) |
PubMed | Abstract | RScore(About this table) | |
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19009284 | Yan X, Feng C, Chen Q, Li W, Wang H, Lv L, Smith GW, Wang J: Effects of sodium fluoride treatment in vitro on cell proliferation, apoptosis and caspase-3 and caspase-9 mRNA expression by neonatal rat osteoblasts. Arch Toxicol. 2009 May;83(5):451-8. Epub 2008 Oct 21. |
13(0,0,2,3) | Details |
16136339 | Zhan XA, Wang M, Xu ZR, Li WF, Li JX: Evaluation of caspase-dependent apoptosis during -induced liver lesion in pigs. Arch Toxicol. 2006 Feb;80(2):74-80. Epub 2005 Sep 1. The obvious DNA ladder and the significantly increased both hepatic caspase-9 and caspase-3 activity indicated that induced caspase-dependent apoptosis in vivo. |
2(0,0,0,2) | Details |
14981920 | Morshed SR, Tokunaga T, Otsuki S, Takayama F, Satoh T, Hashimoto K, Yasui T, Okamura M, Shimada J, Kashimata M, Sakagami H: Effect of antitumor agents on cytotoxicity induction by sodium fluoride. . Anticancer Res. 2003 Nov-Dec;23(6C):4729-36. Caspase 8 (involved in non-mitochondrial extrinsic pathway) and caspase 9 (involved in mitochondrial intrinsic pathway) were also activated, but to a much lesser extent. |
1(0,0,0,1) | Details |
19322641 | Agarwal R, Mumtaz H, Ali N: Role of inositol polyphosphates in programmed cell death. Mol Cell Biochem. 2009 Aug;328(1-2):155-65. Epub 2009 Mar 26. Additionally, we measured changes in AKT phosphorylation, cleavage of caspase-3 and caspase-9, and release of cytochrome C from mitochondria into cytosol. |
1(0,0,0,1) | Details |
18069112 | Lee JH, Jung JY, Jeong YJ, Park JH, Yang KH, Choi NK, Kim SH, Kim WJ: Involvement of both mitochondrial- and death receptor-dependent apoptotic pathways regulated by Bcl-2 family in sodium fluoride-induced apoptosis of the human gingival fibroblasts. Toxicology. 2008 Jan 20;243(3):340-7. Epub 2007 Nov 4. In addition, NaF increased the level of cytochrome c released from the mitochondria into the cytosol, enhanced the caspase-9, -8 and -3 activities, the cleavage of poly (ADP- polymerase (PARP), and up-regulated the voltage-dependent anion channel (VDAC) 1. |
1(0,0,0,1) | Details |
16309196 | Takeuchi R, Hoshijima H, Onuki N, Nagasaka H, Chowdhury SA, Kawase M, Sakagami H: Effect of anticancer agents on codeinone-induced apoptosis in human cancer cell lines. Anticancer Res. 2005 Nov-Dec;25(6B):4037-41. The cytotoxic activity of codeinone against HSC-2 cells was inhibited by N-acetyl- but somewhat additively stimulated by peroxide, sodium fluoride, 5-fluorouridine, cisplatin, doxorubicin and methotrexate. |
0(0,0,0,0) | Details |