| Name | RhoGAP |
|---|---|
| Synonyms | ARHGAP 1; ARHGAP1; CDC42 GTPase activating protein; CDC42GAP; GTPase activating protein rhoOGAP; RHOGAP; RHOGAP 1; RHOGAP1… |
| Name | sodium fluoride |
|---|---|
| CAS | sodium fluoride (NaF) |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 9482864 | Vincent S, Brouns M, Hart MJ, Settleman J: Evidence for distinct mechanisms of transition state stabilization of GTPases by Proc Natl Acad Sci U S A. 1998 Mar 3;95(5):2210-5. Herein, we report that p190 RhoGAP forms a high-affinity complex with Rho GTPases in the presence of ions, suggesting that p190 also functions to stabilize the GTPase transition state. |
1(0,0,0,1) | Details |
| 10494860 | Vincent S, Settleman J: Inhibition of RhoGAP activity is sufficient for the induction of Rho-mediated actin reorganization. Eur J Cell Biol. 1999 Aug;78(8):539-48. We observed that exposure of cultured fibroblasts to sodium fluoride (NaF) results in a rapid and potent stimulation of actin stress fiber formation. |
5(0,0,0,5) | Details |
| 15958199 | Li Y, Decker S, Yuan ZA, Denbesten PK, Aragon MA, Jordan-Sciutto K, Abrams WR, Huh J, McDonald C, Chen E, MacDougall M, Gibson CW: Effects of sodium fluoride on the actin cytoskeleton of murine ameloblasts. Arch Oral Biol. 2005 Aug;50(8):681-8. Epub 2005 Feb 1. In fibroblasts, the Arhgap gene encodes a RhoGAP, which regulates the small G protein designated RhoA. |
2(0,0,0,2) | Details |
| 10555980 | Graham DL, Eccleston JF, Chung CW, Lowe PN: -dependent binding of small G proteins to their GTPase-activating proteins. Biochemistry. 1999 Nov 9;38(45):14981-7. Here, equilibrium binding has been measured using scintillation proximity assays to provide quantitative information on the -mediated interaction of Ras and Rho proteins with their respective GAPs, neurofibromin (NF1) and RhoGAP. |
2(0,0,0,2) | Details |