Protein Information

Name CA3
Synonyms CA III; Carbonic anhydrase C; CA3; CAIII; Car3; Carbonate dehydratase III; Carbonic anhydrase 3; Carbonic anhydrase III…

Compound Information

Name sodium fluoride
CAS sodium fluoride (NaF)

Reference List

PubMed Abstract RScore(About this table)
11938978 Zhang Z, Xu X, Shen X, Xu X: [Effect of fluoride exposure on synaptic structure of brain areas related to learning-memory in mice]. Wei Sheng Yan Jiu. 1999 Jul;28(4):210-2.

The learning-memory behavior was tested in mice on a Y-maze after drinking different concentration of sodium fluoride.
The impairment on the structure of Gray 1 synaptic interface in the CA3 area of mice hippocampus were quantitatively analyzed by electron microscopy and computer image processing appliance.
1(0,0,0,1) Details
12622200 Bhatnagar M, Rao P, Sushma J, Bhatnagar R: Neurotoxicity of fluoride: neurodegeneration in hippocampus of female mice. Indian J Exp Biol. 2002 May;40(5):546-54.

Light microscopic study of hippocampal sub-regions demonstrated significant number of degenerated nerve cell bodies in the CA3, CA4 and dentate gyrus (Dg) areas of sodium fluoride administered adult female mice.
7(0,0,1,2) Details
8625460 Jansen LA, Jongen WM: The use of initiated cells as a test system for the detection of inhibitors of gap junctional intercellular communication. Carcinogenesis. 1996 Feb;17(2):333-9.

To study the potential differences in susceptibility of cells representing different stages in the process of tumor formation, the effect of the selected tumor promoters on GJIC was also investigated in primary mouse keratinocytes and in a mouse skin carcinoma-derived cell line (CA3/7).
Finally sodium fluoride (NaF), whose carcinogenic property is still unclear, was tested for its effects on GJIC in the 3PC cell line.
4(0,0,0,4) Details
12525083 Zhang Z, Shen X, Xu X: [Effects of selenium on the damage of learning-memory ability of mice induced by fluoride]. Wei Sheng Yan Jiu. 2001 May;30(3):144-6.

Sodium fluoride added with or without sodium selenite in deionized water was administered to male mice for 8 weeks.
The influences of fluoride on learning-memory behavior were tested on Y-maze, and the ultrastructure of Gray I synaptic interface in the CA3 area hippocampus was quantitatively analyzed by electron microscopy and computer image processing appliance.
1(0,0,0,1) Details